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J Med Virol ; 56(4): 337-41, 1998 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-9829639

RESUMO

This study investigated the frequency of mild or asymptomatic measles infections among 44 persons exposed to a student with measles during a 3-day bus trip using two buses. Questionnaires and serum samples were obtained 26-37 days after the trip. All participants had detectable measles-neutralizing antibodies, and none developed classic measles symptoms. Ten persons (23%) were IgM positive for measles, indicating recent infection. Among previously vaccinated IgM-negative persons, those who rode on bus A with the index case-patient had significantly higher microneutralization titers than those on bus B (P= .001), suggesting that some persons on bus A were infected but were IgM negative at the time of the study. Mild or asymptomatic measles infections are probably very common among measles-immune persons exposed to measles cases and may be the most common manifestation of measles during outbreaks in highly immune populations.


Assuntos
Vacina contra Sarampo/imunologia , Vírus do Sarampo/imunologia , Sarampo/epidemiologia , Sarampo/imunologia , Adolescente , Adulto , Idoso , Anticorpos Antivirais/sangue , Surtos de Doenças , Humanos , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Sarampo/patologia , Pessoa de Meia-Idade
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