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1.
Crit Care Explor ; 6(6): e1102, 2024 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-38842419

RESUMO

BACKGROUND: Tracheostomy-related acquired pressure injuries (TRPIs) are one of the hospital-acquired conditions. We hypothesize that an uneven ventilator circuit load, leading to non-neutral tracheostomy tube positioning in the immediate post-tracheostomy period, leads to an increased incidence of TRPIs. Does switching the ventilator circuit load daily, in addition to standard post-tracheostomy care, lead to a decreased incidence of TRPIs? METHODS: This is a prospective quality improvement study. Study was conducted at two academic hospital sites within tertiary care hospitals at Emory University in different ICUs. Consecutive patients undergoing bedside percutaneous tracheostomy by the interventional pulmonary service were included. The flip the ventilator circuit (FLIC) protocol was designed and implemented in selected ICUs, with other ICUs as controls. RESULTS: Incidence of TRPI in intervention and control group were recorded at post-tracheostomy day 5. A total of 99 patients were included from October 22, 2019, to May 22, 2020. Overall, the total incidence of any TRPI was 23% at post-tracheostomy day 5. Incidence of stage I, stage II, and stages III-IV TRPIs at postoperative day 5 was 11%, 12%, and 0%, respectively. There was a decrease in the rate of skin breakdown in patients following the FLIC protocol when compared with standard of care (13% vs. 36%; p = 0.01). In a multivariable analysis, interventional group had decreased odds of developing TRPI (odds ratio, 0.32; 95% CI, 0.11-0.92; p = 0.03) after adjusting for age, albumin, body mass index, diabetes mellitus, and days in hospital before tracheostomy. CONCLUSIONS: The incidence of TRPIs within the first week following percutaneous tracheostomy is high. Switching the side of the ventilator circuit to evenly distribute load, in addition to standard bundled tracheostomy care, may decrease the overall incidence of TRPIs.


Assuntos
Úlcera por Pressão , Traqueostomia , Humanos , Traqueostomia/efeitos adversos , Traqueostomia/métodos , Traqueostomia/instrumentação , Masculino , Feminino , Estudos Prospectivos , Pessoa de Meia-Idade , Idoso , Úlcera por Pressão/prevenção & controle , Úlcera por Pressão/etiologia , Úlcera por Pressão/epidemiologia , Incidência , Respiração Artificial/efeitos adversos , Melhoria de Qualidade , Unidades de Terapia Intensiva , Ventiladores Mecânicos/efeitos adversos
2.
Curr Opin Pulm Med ; 30(1): 25-34, 2024 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-37851368

RESUMO

PURPOSE OF REVIEW: Appropriate staging is of utmost importance in nonsmall cell lung cancer (NSCLC), as the pathologic stage dictates both overall prognosis and appropriate therapeutic pathways. This article seeks to review the current recommendations for mediastinal staging of NSCLC and available modalities to achieve this. Landmark publications pertaining to recent advancements in NSCLC treatments are also highlighted and the role of specific bronchoscopic modalities for tissue acquisition are reviewed. RECENT FINDINGS: Recent advancements in the treatment of NSCLC have made accurate mediastinal staging more important than ever. Guidelines and recommendations outlining patients that warrant invasive mediastinal staging are available and a systematic approach should be utilized when sampling is performed. Ensuring the adequacy of tissue for the growing number of molecular biomarkers that must be tested has been the focus of many recent studies. SUMMARY: Appropriate mediastinal staging is crucial for the management of patients with NSCLC as is obtaining adequate tissue for diagnostic and therapeutic purposes. EBUS-TBNA is sufficient for the diagnosis of nonsmall cell and small cell lung carcinomas, but EBUS-guided intranodal forceps and cryobiopsy may provide more optimal specimen for patients with benign disease, such as sarcoidosis, or in cases of lymphoma. Further studies are necessary to better delineate the role of these techniques in the diagnosis and staging of mediastinal diseases before they become the primary diagnostic modalities.


Assuntos
Carcinoma Pulmonar de Células não Pequenas , Neoplasias Pulmonares , Carcinoma de Pequenas Células do Pulmão , Humanos , Carcinoma Pulmonar de Células não Pequenas/patologia , Neoplasias Pulmonares/patologia , Mediastino/diagnóstico por imagem , Aspiração por Agulha Fina Guiada por Ultrassom Endoscópico , Estadiamento de Neoplasias , Linfonodos , Broncoscopia/métodos
4.
Med Educ Online ; 26(1): 1924350, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33960914

RESUMO

Ultrasound (US)-guided central venous catheter (CVC) insertion is a procedure that carries the risk of significant complications. Simulation provides a safe learning atmosphere, but most CVC simulators are not available outside of simulation centers. To explore longitudinal trends in US-guided CVC insertion competency in internal medicine (IM) interns, we studied the use of a low-fidelity, gelatin-based, US-guided CVC insertion simulation model combined with a simulation curriculum. This prospective observational study of IM interns was performed over the course of one academic year. Interns (n = 56) underwent model-based, US-guided procedure simulation training program and a repeated training course prior to their intensive care unit (ICU) rotation. CVC insertion competency at different timepoints was recorded. Survey data about intern experience and attitudes were also collected. Out of the 56 interns initially trained, 40 were included in the final analysis. Across all outcomes, interns experienced skill atrophy between initial training and the beginning of their ICU month. However, by the end of the month, there was a significant improvement in competency as compared to initial procedural training, which then waned by the end of the intern year. Attitudes toward the model were generally positive and self-reported confidence improved throughout the course of the year and correlated with objective measures of competency. Over the course of their intern year, which included simulation training using a gelatin-based model, interns demonstrated consistent competency trends. The use of a gelatin-based CVC insertion simulation model warrants further study as an adjunctive aid to existing simulation training.


Assuntos
Cateterismo Venoso Central/métodos , Medicina Interna/educação , Internato e Residência/métodos , Treinamento por Simulação/métodos , Ultrassonografia de Intervenção/métodos , Adulto , Competência Clínica , Currículo , Feminino , Gelatina , Humanos , Masculino , Sistemas Automatizados de Assistência Junto ao Leito , Estudos Prospectivos
5.
Transpl Infect Dis ; 19(3)2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28199763

RESUMO

We report the case of an afebrile 59-year-old heart transplant recipient presenting with nausea, vomiting, diarrhea, weight loss, and diffuse lymphadenopathy. Lymph node biopsies revealed non-caseating granulomatous inflammation. Cat-scratch disease was confirmed by serologic studies, Warthin-Starry staining, and polymerase chain reaction testing of lymph node tissue. The patient's symptoms resolved with 3 months of doxycycline. We review clinical presentations of Bartonella henselae infection and review diagnostic approaches for B. henselae in this patient population.


Assuntos
Antibacterianos/uso terapêutico , Bartonella henselae/isolamento & purificação , Cardiomiopatias/cirurgia , Doença da Arranhadura de Gato/microbiologia , Transplante de Coração/efeitos adversos , Imunossupressores/efeitos adversos , Biópsia , Temperatura Corporal , Doença da Arranhadura de Gato/complicações , Doença da Arranhadura de Gato/tratamento farmacológico , Doença da Arranhadura de Gato/patologia , Diarreia/tratamento farmacológico , Diarreia/etiologia , Diarreia/microbiologia , Doxiciclina/uso terapêutico , Humanos , Linfonodos/diagnóstico por imagem , Linfonodos/patologia , Masculino , Pessoa de Meia-Idade , Náusea/tratamento farmacológico , Náusea/etiologia , Náusea/microbiologia , Reação em Cadeia da Polimerase , Testes Sorológicos , Tomografia Computadorizada por Raios X , Redução de Peso
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