RESUMO
The selection of antibiotic resistant Pseudomonas aeruginosa strains by an indiscriminate administration of antibiotics has been observed. The consequences induced by Ps. aeruginosa on the tissue culture cell lines (both primary and continuos) are harmful, velding a sharp pH drop from a slight initial increase, followed by the destruction of the cell layer. Sometimes the cells succeed in growing up for some passages since antibiotics are usually present in the growth medium. Tissue culture contamination can be avoided by carrying out drastic disinfection treatments. A profilatic measure would amply to keep the Virology laboratories separated from the rest of the hospital in which Ps. aeruginosa is often present.
Assuntos
Técnicas de Cultura , Pseudomonas aeruginosa , Portador Sadio/epidemiologia , Linhagem Celular , Departamentos Hospitalares , Humanos , Itália , Recursos Humanos em Hospital , Infecções por Pseudomonas/epidemiologia , VirologiaRESUMO
Salmonella wien was detected in various patients admitted to the D. Cotugno Hospital between May 1974 and June 1975. Strains isolated in Naples showed the same in vitro transferable resistance to antibiotics as those responsible for the recent epidemics in Algeria and France.
Assuntos
Enterite/epidemiologia , Infecções por Salmonella/epidemiologia , Argélia , Antibacterianos/uso terapêutico , Resistência Microbiana a Medicamentos , Enterite/tratamento farmacológico , Enterite/etiologia , Feminino , Humanos , Itália , Masculino , Infecções por Salmonella/tratamento farmacológicoAssuntos
Ampicilina/administração & dosagem , Cloranfenicol/administração & dosagem , Sulfametoxazol/administração & dosagem , Trimetoprima/administração & dosagem , Febre Tifoide/tratamento farmacológico , Adolescente , Adulto , Ampicilina/uso terapêutico , Criança , Pré-Escolar , Cloranfenicol/uso terapêutico , Quimioterapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sulfametoxazol/uso terapêutico , Trimetoprima/uso terapêuticoRESUMO
During the cholera epidemic in 1973, nine contact carriers of Vibrio cholerae El Tor serotype Ogawa were identified in a family from Naples as well as six others coming from different parts of the city or its surroundings. All the subjects were admitted to the quarantine ward of the 'Cotugno Hospital' (Naples) in which they remained continuously for 14 or 16 days. During this time these bacteriologically confirmed carriers were treated orally with a long-acting sulphonamide (sulphamethoxypyrazine, Kelfizine). Coprocultural examinations carried out on each patient on average 7 times after the treatment over a period of 6 months, proved the absence of V. cholerae. Serological tests also showed high levels of agglutinating and vibriocidal anticholera Ogawa antibodies in two unvaccinated carriers.