Introduction of a Pathophysiology-Based Diagnostic Decision Support System and Its Potential Impact on the Use of AI in Healthcare.

Many currently available Diagnostic Decision Support Systems (DDSS) are based on causal condition-symptom relations that exhibit certain shortcomings. Ada's new approach explores the capabilities of DDSS based on pathophysiology, describing a disease as a dynamically evolving process. We generated a pathophysiology model for 8 conditions and 68 findings suitable to assess this approach. Preliminary results meet our expectations while leaving space for further improvement.