RESUMO
Background: : : Oral neoplasms are common in cats. Just the percentage of oral squamous cell carcinoma (SCC) accounts for about 70% of all feline oral tumors also it is considered highly invasive and malignant. There are reports that the flea collar increases five times the risk oral SCC development. In addition, smoke exposure is also considered a risk factor, and the animals were exposed to tobacco when makes it self-cleaning. SCC well differentiated is characterized histologically by numerous keratin pearls formation and clearly evident intercellular bridges with poor mitotic activity and nuclear pleomorphism. The median age of cats with oral SCC is about 11-13 years, but, cats as young as three years and as old as twenty-one years have been previously reported. However, it was not found reports of oral SCC in cats at age younger than one year old. The aim of this article is reports one case of oral SCC feline at age of three months old. Five days after surgical procedure the patient returned to the veterinary and the owner report that it returned to eating well. Case: It was exanimate a three months old male mixed breed cat presenting oral volume increased and the biopsy test was suggested. However, the owner returned 3 months later when the animal showed tumor 6 cm in diameter, dysphagia, tongue protrusion, excessive salivation, halitosis and weight loss. It was indicate
RESUMO
Background: : : Oral neoplasms are common in cats. Just the percentage of oral squamous cell carcinoma (SCC) accounts for about 70% of all feline oral tumors also it is considered highly invasive and malignant. There are reports that the flea collar increases five times the risk oral SCC development. In addition, smoke exposure is also considered a risk factor, and the animals were exposed to tobacco when makes it self-cleaning. SCC well differentiated is characterized histologically by numerous keratin pearls formation and clearly evident intercellular bridges with poor mitotic activity and nuclear pleomorphism. The median age of cats with oral SCC is about 11-13 years, but, cats as young as three years and as old as twenty-one years have been previously reported. However, it was not found reports of oral SCC in cats at age younger than one year old. The aim of this article is reports one case of oral SCC feline at age of three months old. Five days after surgical procedure the patient returned to the veterinary and the owner report that it returned to eating well. Case: It was exanimate a three months old male mixed breed cat presenting oral volume increased and the biopsy test was suggested. However, the owner returned 3 months later when the animal showed tumor 6 cm in diameter, dysphagia, tongue protrusion, excessive salivation, halitosis and weight loss. It was indicate
RESUMO
PURPOSE: Evaluate experimental urethral defects reconstruction in dogs through implantation of tubular oral autologous mucosa fragments. METHODS: About 2 cm of penile urethra was resected. The induced defect was repaired through anastomosis of tubular oral autologous mucosa fragment extracted from the lower lip. RESULTS: 14 (70%) of the operated dogs showed normal urinary flow and 6 (30%) revealed stenosis which was revealed by radiological examination carried out at 60 days post-operative. Necropsy findings showed the integrity of the implants to the urethral sulcus, and histological findings confirmed that the implanted fragments were covered by the urethral epithelium and inflammatory infiltration of neutrophils, lymphocytes and macrophages was present. CONCLUSION: Implantation of tubular oral autologous mucosa fragments is adequate to reconstruct urethral iatrogenic defects in dogs, although it may result in post-operative stenosis.
OBJETIVO: Avaliar a reconstrução de defeitos experimentais na uretra do cão com a implantação de segmentos tubulares de mucosa bucal autóloga. MÉTODOS: Procedeu-se à ressecção de cerca de 2 cm da uretra peniana de 20 cães. O defeito produzido foi corrigido por meio da anastomose de fragmento tubular de mucosa bucal autóloga, seccionado do lábio inferior. RESULTADOS: Entre os animais operados, 14 (70%) apresentaram jato urinário normal e seis (30%) evidenciaram estenose confirmada por meio de exame radiológico realizado aos 60 dias do pós-operatório. Durante a necrópsia verificou-se a integridade dos implantes no sulco uretral, associado a infiltrado inflamatório de neutrófilos, linfócitos piócitos e histiócitos. As análises histológicas revelaram que os fragmentos implantados estavam recobertos pelo epitélio uretral. CONCLUSÃO: A implantação de segmentos autólogos de mucosa bucal é adequada para a reconstrução de defeitos uretrais iatrogênicos no cão, embora possa resultar em estenose pós-operatória.
RESUMO
Oral mucosa has been considered an excellent alternative method to substitute for urethral tissue. OBJECTIVE: To investigate the results of a triangulation of an end-to-end anastomosis using oral mucosa for urethral reconstruction. METHODS: Twelve healthy dogs of no defined race weighing between 13 and 17 kg were anesthetized and an urethral catheter was maintained during the whole surgery. First, a piece of oral mucosa was removed from the superior lip and kept in saline solution containing aqueous chloramphenicol. Then, a 2 cm fragment of the urethra from the penis was removed and the oral mucosa was used to reconstruct the urethra. RESULTS: After 60 days we observed stenosis in 25% of the dogs. There were also urethral-cutaneous fistulas and constrast leakage at the site of anastomosis. CONCLUSION: The triangulation of an end-to-end anastomosis using oral mucosa for urethral reconstruction does not prevent the occurrence of stenosis.
O uso da mucosa bucal para tratar a estenose uretral tem sido considerado um excelente método alternativo para substituir o tecido uretral. OBJETIVO: Investigar os resultados da realização da triangulação da anastomose término-terminal de fragmento de mucosa bucal na reconstrução uretral. MÉTODOS: Foram utilizados 12 cães entre 13 e 17 Kg, sem raça definida, aparentemente sadios. Após anestesia, introduziu-se sonda na uretra dos animais que foi mantida durante todo ato operatório. Inicialmente procedeu-se a ressecção de um fragmento de mucosa bucal do lábio superior e imerso em solução salina com cloranfenicol aquoso. A seguir procedeu-se a exposição da uretra peniana e ressecou-se um segmento de dois centrímetros. Foi realizada a triangulação da anastomose término-terminal do fragmento de mucosa bucal na reconstrução uretral. RESULTADOS: Após 60 dias observou-se a ocorrência de estenose em 25% dos animais. Foram observadas fístulas uretro-cutâneas e extravasamento de contraste no local das anastomoses. CONCLUSÃO: A triangulação da anastomose término-terminal de fragmento de mucosa bucal na reconstrução uretral não evita a ocorrência de estenose.