1.
Eur J Med Chem
; 86: 81-6, 2014 Oct 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25147149
RESUMO
A gallium(III) complex with 7-chloroquinoline thiosemicarbazone was synthesized and characterized. The complex proved to be thirty-one times more potent on colon cancer cell line, HCT-116, with considerably less cytotoxicity on non-cancerous colon fibroblast, CCD-18Co, when compared to etoposide. Its anti-malarial potential on 3D7 isolate of Plasmodium falciparum was better than lumefantrine.