VITAMIN D LEVEL AND ITS LINK WITH VISUAL ACUITY AND CONTRAST SENSITIVITY IN PATIENTS WITH AGE-RELATED MACULAR DEGENERATION.

OBJECTIVE: The aim: Determination of vitamin D level and its connection with visual functions in patients with age-related macular degeneration, dry form. PATIENTS AND METHODS: Materials and methods: We analyzed the data of studies (25(OH)D3 levels (nmol/l), LogMAR visual acuity and Logarithmic contrast sensitivity) of 2 groups of women of postmenopausal age: 1 group (58 people - 58 eyes) - patients with age-related macular degeneration (dry form) - study group; 2 group (29 people - 29 eyes) - people without ophthalmic pathology - control group. RESULTS: Results: In the study group, 37 patients (63,8%) had vitamin D deficiency, 21 people (36,2%) had vitamin D insufficiency. In the control group, these figures were 69% and 31%, respectively. These indicators were defined as low (the normal supply of vitamin D is considered to be 100 nmol/l and more). Visual acuity due to ETDRS chart in the study group was 0,22±0,04 (in patients with vitamin D deficiency) and 0,12±0,03 (in patients with vitamin D insuffi¬ciency), in the control group - 0,13±0,04 and 0,05±0,04 respectively. In the control group, the logarithmic values of contrast sensitivity (log CS) were 1,58±0,04 log CS (in patients with vitamin D deficiency) and 1,62±0,02 log CS (in patients with vitamin D insufficiency). For patients from the study group, these figures were reduced to 0,98±0,1 log CS and 1,10±0,06 log CS respectively. CONCLUSION: Conclusions: Patients with age-related macular degeneration, dry form, have low levels of vitamin D, with a predominance of its deficiency. It has been determined that with age-related macular degeneration, functional losses are observed when perceiving objects of low contrast.

The Development and Status of Eye Banking with Special Focus on the Commitment of LIONS Clubs. / Entwicklung und Stand des Hornhautbankings unter besonderer Berücksichtigung des Engagements von LIONS Clubs.

BACKGROUND: Ever since the first successful keratoplasty in 1905, there has been a need to store corneas for transplantation. R. Townley Paton founded the first eye bank in New York in 1944. With Helen Keller's call in 1925 for LIONS to "constitute themselves Knights of the Blind in the crusade against darkness", LIONS Clubs International has become involved in the establishment of eye banks worldwide. This paper presents the development of eye banking in general and with special attention to the support offered by LIONS Clubs. METHODS: Selective literature search through PubMed, Google Scholar and Google in close cooperation with the LIONS Eye Banks already established in Germany, LIONS Clubs International (USA) and the Julius Hirschberg Society (Austria). Analysis focused on the founding processes of 6 German eye banks and their current services. RESULTS: Filatov was the first to keep donor eyes in a cool, moist container for a few days. In 1973, Summerlin et al described the technique of organ culture for donor corneas, and McCarey & Kaufman described a liquid storage medium in 1974. LIONS Clubs International and their organisational structure first supported an eye bank in the US in 1952, outside America in Hong Kong in 1962 and in Germany in 1969. Funding is provided across all levels of LIONS as network support and material resources. In general, staff funding is not provided. Of the 88 eye banks operating worldwide today, 44 are called LIONS Eye Banks. 6 of the current 26 eye banks in Germany are operating under LIONS sponsorship and run by departments of ophthalmology at university medical centres. Although the number of transplants has increased in recent years due to new surgical techniques, the number of patients waiting for donor tissue is also growing as a result of the broadening indication. CONCLUSIONS: Even today, the availability of donor corneas limits patient care. Eye banks help to meet the need for donor corneas. However, the techniques and technical equipment of eye banks must undergo continuous improvement. The local, national and international network of LIONS Clubs can assist in establishing these in order to facilitate legal requirements and structural developments. This support frequently lasts for many years, often triggers additional public commitment and is thus also a supporting element for the future development of eye banking in Germany.

[Calculating the Human Eye - The Evolution of Biometry for Cataract Surgery]. / Die Berechnung des menschlichen Auges ­ zur Evolution der Biometrie in der Kataraktchirurgie.

INTRODUCTION: Optical biometry is the standard diagnostic tool and essential basis for IOL calculation prior to cataract surgery today. Our article will provide a short overview of the historical development of biometry of the human eye and the formulas used for IOL calculation. MATERIAL AND METHODS: Selective literature search in books and journal articles via PubMed, Google Scholar and Google as well as close cooperation with IOLCon at Saarland University, Homburg/Saar (Germany). RESULTS: For first measurements of the eye, ultrasound was applied invasively. Today, ultrasound is mostly restricted to cases where optical biometry cannot be performed due to opaque optical media. However, today, most of the modern biometers are working with OCT non-invasively. Along with this technical evolution, numerous formulas have been developed for calculating the optical power of each respective IOL. Intraocular lenses can be calculated with different strategies: with empirical formulas, the IOL power is derived from a series of biometric data without any anatomical or physical background. With the theoretical-optical formulas, which are most commonly used today, the IOL power is extracted from a paraxial optical model which simplifies the eye to linear Gaussian optics. With modern raytracing settings, the Snell's law is applied at each refracting surface within the eye and the best focus position is compared with the position of the fovea. CONCLUSIONS: Today, an increasing number of eyes that underwent refractive surgery previously are facing cataract surgery. Maybe even more important than adequate biometry of the human eye will be using appropriate calculation schemes in order to enhance post-cataract refractive outcomes or predictability.

Lights and darks of a picture. The life of Giovanni Francesco Barbieri, "il Guercino" - the squinter.

PURPOSE: To be cross-eyed is a wide-spread dysfunction of the eye and squinting is currently regarded as unattractive. However, in ancient times, societies saw squinting as a sign of piety or even beauty. Even Venus was depicted heterophoric quite often. The most famous artist who was cross-eyed was Giovanni Francesco Barbieri (*08.02.1591; †22.12.1666, both Italy). His nickname was "Il Guercino" which means "the squinter." This article reflects on vision and art from the perspective of a cross-eyed person. METHODS: Life and work of Giovanni Francesco Barbieri was analyzed and interpreted based on selective literature research of books and journal articles via PubMed, Google Scholar, and Google. RESULTS: As squinters use mostly only one eye as the other eye is amblyopic, it could be expected that their paintings would be more or less two dimensional. Already at the age of seven, Barbieri showed great talent in drawing and painting. At age 17, he started his education at the famous Bologna school. Barbieri was very productive, leaving behind, at his death,106 large altarpieces and 144 other paintings. During his lifetime, he was well accepted, sought after, and quite wealthy. In analyzing a selection of Barbieri's work, one is amazed at how detailed the artist was in depicting chiaroscuro in his paintings to present a three-dimensional picture. CONCLUSIONS: Barbieri did not make a secret of the dysfunction of his eyes. In contrast, he showed his squinting eye distinctly in his famous self-portrait from ca. 1635. It can be assumed that "Il Guercino" was so detailed in studying light and shadow with his one eye that he could compensate for his amblyopic eye. By this, Barbieri could create pictures with an amazing degree of variations of light and shadow.

From Reading Stones, Glasses and Contact Lenses to Intraocular Lenses & Ophthalmic Lasers--A Short Overview over the History of Visual Aids.

Alhazen, ibn al-Haytham, (965 Basra - c. 1040 in Cairo) was a Muslim polymath who made significant contributions to the principles of optics, being the first to recognize the optical effect by transparent objects in the 11th century. His insights led to a fundamental revolution, enabling older presbyopic persons to read again. Today many more options are available to help visually impaired people correct their sight defects. This article will give an historical overview of the sight aids which are available today and will describe the very first beginnings of the development of the "reading stone" or "glasses". Further, it will also give a chronological overview of more modern techniques, e.g., intraocular lenses, contact lenses and the options of refractive surgery.