[Meralgia paresthesia should also be considered in coxarthrosis]. / Bei Koxarthrose auch an die Meralgia paraesthetica denken!

Due to its variable attitude--and motiondepending pain symptoms meralgia paraesthetica may easily be misinterpreted as an affection of the hip joint or not be regarded as additional and sometimes chief complaint of that. Moreover our investigations show that meralgia paraesthetica is seen quite frequently in patients suffering from coxarthrosis. A case report illustrates the subject. Finally diagnostic and therapeutic proceedings are suggested.

[Course of treatment of a luxation of the 4th and 5th carpometacarpal joint with hamate involvement]. / Behandlungsverlauf einer Luxation in den Karpometakarpalgelenken IV und V unter Hamatumbeteiligung.

An uncommon case of a closed dorsal dislocation of the fourth and fifth metacarpal bases associated with a flake fracture of the hamate bone is described because of the rarity of this injury. In order to regain full function, an open reduction was necessary. Stability of the carpometacarpal joints was achieved by osteosynthesis using a Kirschner wire.

The biphasic fluence response of carotenogenesis in Neurospora crassa: Temporary insensitivity of the photoreceptor system.

Whether or not illumination is continuous or interrupted during the span in which increasing illumination time periods (i.e., increasing fluences) have no different effect on carotenogenesis is optional, in regard to the amount of carotenoids produced (revealing the plateau of the biphasic fluence response curve). This indicates temporary insensitivity. When the time delay between the onsets of the initial and second illumination is extended beyond the expanse of the plateau, the amount of carotenoids induced by the second illumination depends on the time elapsed following the first exposure; after ca. 2 h, maximum competence for a second induction is completely restored. On the other hand, the amount of carotenoids induced by a second illumination also depends on the duration of this second illumination, but, unlike the dependence in a single illumination, results in a different fluence response curve for the second exposure. When UV-A is used for induction, the refractory period which follows the first exposure seems to be the same as for blue light, suggesting vision of UV-A and blue light by the same photoreceptor system.

Fluence response relationship of carotenogenesis inNeurospora crassa.

The fluence response of the blue light induced carotenoid synthesis inNeurospora is biphasic. Using fluence rates between 0.3 and 40 Wm(-2), increasing illumination times beyond 16 min (at 20°C) result in a second rise of the amount of carotenoids synthesized in the subsequent dark period. On altering the temperature, the transition point to the second phase of the response is shifted to shorter/longer illumination periods with increasing/decreasing temperature, respectively. The transition point can also be shifted by administering high fluence rates of near UV light: The start of the second phase is already triggered after an irradiation time of 2 min. The findings suggest that elements of the transduction sequence become depleted and senstivity recovers in a temperature-dependent process. The biphasic response and the effects of UV light are discussed in relation to the transduction mechanism and to the ecological significance.

Evidence for a photoinduced synthesis of poly(A) containing mRNA in Fusarium aquaeductuum.

Based on inhibitor studies it has been concluded that in photoregulated processes of plant development, light induces differential gene expression. Using affinity chromatography of double labelled polysomal RNA on poly(U)-sepharose 4B, we were able to demonstrate different (3)H/(14)C ratios for the bound poly(A) containing fraction (mRNA) when compared with the unbound fraction: when [(3)H]uridine was present in the light induced sample and [(14)C]uridine in the dark control, in the bound material the (3)H/(14)C ratio was found to be higher than in the unbound fraction and vice versa. No such shift was observed, when both sample and control were kept in the dark. Our data are interpreted to provide evidence for photoinduced de novo synthesis of mRNA.