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1.
J Occup Environ Med ; 2024 Jun 06.
Artigo em Inglês | MEDLINE | ID: mdl-38845099

RESUMO

OBJECTIVES: Employee Whole Health (EWH) empowers VA employees to take charge of their well-being by integrating self-care into their workday, but employees lack time to participate. METHODS: Employees at three VA medical centers participated in a 12-month feasibility cohort study to protect 60 minutes of time per week for self-care. Questionnaire data was collected at three time points; qualitative data at two time points. Pilot offerings included education and complementary and integrative health modalities for well-being. RESULTS: Employees enrolled spring 2021 (n = 312). Complete-case regression analyses indicated significant improvements in wellness culture, resiliency, self-efficacy, perceived stress, and flourishing at twelve months. Multiple imputation analyses confirmed improvements except for self-efficacy. Qualitative findings supported quantitative findings. CONCLUSIONS: Providing protected time for self-care was feasible and supported improvements in well-being. However, high workload was identified as an ongoing barrier to participation.

2.
J Occup Environ Med ; 66(4): e131-e136, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38588074

RESUMO

OBJECTIVE: The aim of the study is to examine how involvement in the Whole Health System of care, clinically and personally (through employee-focused activities), would affect employee satisfaction, engagement, burnout, and turnover intent in the Veterans Health Administration. METHODS: Multivariate logistic regression analysis of cross-sectional survey from Veterans Health Administration employees was used to determine the influence of Whole Health System involvement and Employee Whole Health participation on job attitudes. RESULTS: Whole Health System involvement was associated higher job satisfaction, higher levels of engagement, lower burnout, and lower turnover intent. A similar pattern of results was identified when looking specifically at Employee Whole Health participation and associated job attitudes. CONCLUSIONS: Employees who are either directly involved in delivering Whole Health services to veterans or who have participated in Whole Health programming for their own benefit may experience a meaningful positive impact on their well-being and how they experience the workplace.


Assuntos
Esgotamento Profissional , Veteranos , Humanos , Estudos Transversais , Intenção , Local de Trabalho , Satisfação no Emprego , Reorganização de Recursos Humanos , Inquéritos e Questionários
3.
Glob Adv Health Med ; 10: 21649561211022698, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34104580

RESUMO

The Veterans Health Administration (VHA) is implementing a Whole Health System (WHS) of care that empowers and equips Veterans to take charge of their health and well-being and live their lives to the fullest, and increasingly leaders recognize the need and value in implementing a similar approach to support the health and well-being of employees. The purpose of this paper is to do the following: 1) provide an overview of the WHS of care in VHA and applicability in addressing employee resiliency; 2) provide a brief history of employee well-being efforts in VHA to date; 3) share new priorities from VHA leadership as they relate to Employee Whole Health strategy and implementation; and 4) provide a summary of the impacts of WHS of care delivery on employees. The WHS of care utilizes all therapeutic, evidence-based approaches to support self-care goals and personal health planning. Extending these approaches to employees builds upon 10 years of foundational work supporting employee health and well-being in VHA. In 2017, one facility in each of the 18 Veterans Integrated Service Networks (VISNs) in VHA was selected to participate in piloting the WHS of care with subsequent evaluation by VA's Center for Evaluating Patient-Centered Care (EPCC). Early outcomes, from an employee perspective, suggest involvement in the delivery of the WHS of care and personal use of the whole health approach have a meaningful impact on the well-being of employees and how they experience the workplace. During the COVID-19 pandemic, VHA has continued to support employees through virtual resources to support well-being and resiliency. VHA's shift to this patient-centered model is supporting not only Veteran care but also employee health and well-being at a time when increased support is needed.

4.
Mil Med ; 184(7-8): e218-e224, 2019 07 01.
Artigo em Inglês | MEDLINE | ID: mdl-30793192

RESUMO

INTRODUCTION: Veterans Health Administration (VHA) is undergoing changes in the practice of health care focusing on approaches that prioritize veteran well-being. Given transformation efforts, opportunities exist to enhance the health and well-being of patients and employees alike - a significant proportion of whom are veterans. To date, differences in health status between veteran and civilian employees within VHA have not been examined. MATERIALS AND METHODS: Data from an annual organizational census survey with health promotion module conducted in 2015 were analyzed to estimate the prevalence of health risk behaviors, mental health, and chronic health conditions by veteran status within genders (n = 86,257). To further examine associations by gender between veteran status and health measures controlling for covariates, multivariate logistic regression analyses were utilized. RESULTS: Prevalence estimates generally indicated veterans have worse health status and health risk behaviors than their civilian counterparts. Results from multivariate logistic regression analyses indicated many significant associations between veteran status and health by gender controlling for other important demographic variables and a total comorbidity score. Compared to civilian employees within respective genders, both male and female veteran employees have increased odds of being a current smoker. Both male and female veteran employees have decreased odds of physical inactivity compared to civilian employees. For mental health and chronic health conditions, there are several conditions that veteran employees have increased odds for when compared to civilian employees of like gender; these include low back problems, arthritis, anxiety, depression, and sleep disorders. CONCLUSIONS: Veteran employees in VHA have worse health status than their civilian counterparts on a number of measures of health risk behaviors, mental health, and chronic health conditions. Given current organizational priorities aimed at cultural transformation, the present time is an optimal one to work collaboratively to enhance the health and well-being services that are available for patients and employees alike. All employees, particularly our unique population of veteran employees, will benefit from such an approach.


Assuntos
Nível de Saúde , Veteranos/estatística & dados numéricos , Adulto , Feminino , Disparidades nos Níveis de Saúde , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Prevalência , Inquéritos e Questionários , Estados Unidos , United States Department of Veterans Affairs/organização & administração , United States Department of Veterans Affairs/estatística & dados numéricos
5.
J Occup Environ Med ; 60(11): e582-e588, 2018 11.
Artigo em Inglês | MEDLINE | ID: mdl-30199468

RESUMO

OBJECTIVE: Focus groups were conducted at one veterans affairs (VA) medical center to understand (1) how the work environment and conditions of work influence employee safety, health, and well-being; (2) what programs, policies, and practices promote and protect employee safety and health in VA; and (3) how employee safety, health, and well-being impact the organizational mission. METHODS: Nine focus groups were conducted with leadership, supervisor, and frontline employees. Focus groups were audio recorded, transcribed, and content analysis was performed. RESULTS: Fifty-five employees participated in the focus groups. Six common themes emerged-stressful working conditions, health hazards, organizational factors, current program knowledge, participation barriers, and program suggestions. CONCLUSIONS: Employees identified organizational and structural elements of work that impact safety, health, and well-being. Application of the Total Worker Health™ hierarchy of controls provided a novel framework for discussion of focus group findings.


Assuntos
Hospitais de Veteranos , Exposição Ocupacional , Saúde Ocupacional , Objetivos Organizacionais , Política Organizacional , Recursos Humanos em Hospital , Grupos Focais , Humanos , Estresse Ocupacional/etiologia , Percepção , Recursos Humanos em Hospital/psicologia , Local de Trabalho/psicologia
6.
Stress Health ; 34(4): 490-499, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-29683254

RESUMO

The goals of this paper were twofold: (a) To provide a population overview of burnout profiles by occupation in a large, health care sector employee population and (b) to investigate how burnout profiles relate to self-reported health behaviours, chronic conditions, and absenteeism. Burnout profiles were considered by 5 main occupational groups (physicians, nurses, other clinical, administrative, and wage grade [trade, craft, and labor workers]) in survey respondents (n = 86,257 employees). Logistic regression analyses were conducted to examine how burnout profiles were associated with health controlling for gender, age, race, ethnicity, and occupational group. Employees in the "Frustrated/Burning Up" and "Withdrawing/Burned Out" profiles, respectively, had significantly increased odds of anxiety (OR = 2.17; 99% CI [2.04, 2.31]; OR = 2.21; 99% CI [2.05, 2.38]), depression (OR = 2.06; 99% CI [1.93, 2.20]; OR = 2.20; 99% CI [2.04, 2.38]), sleep disorders (OR = 1.98; 99% CI [1.85, 2.12]; OR = 1.97; 99% CI [1.81, 2.13]), low back disease (OR = 1.60; 99% CI [1.50, 1.71]; OR = 1.58; 99% CI [1.47, 1.70]), physical inactivity (OR = 1.49; 99% CI [1.38, 1.60]; OR = 1.68; 99% CI [1.54, 1.83]), and 5 or more days away from work (OR = 1.74; 99% CI [1.65, 1.85]; OR = 2.15; 99% CI [2.01, 2.30]). Burnout is related to the health of employees. Burnout profiles offer a way to assess patterns of burnout by occupational group and may help customize future interventions.


Assuntos
Ansiedade/epidemiologia , Esgotamento Profissional/epidemiologia , Depressão/epidemiologia , Pessoal de Saúde/estatística & dados numéricos , Dor Lombar/epidemiologia , Comportamento Sedentário , Licença Médica/estatística & dados numéricos , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estados Unidos/epidemiologia , United States Department of Veterans Affairs , Adulto Jovem
7.
J Occup Environ Med ; 58(12): 1217-1222, 2016 12.
Artigo em Inglês | MEDLINE | ID: mdl-27930482

RESUMO

OBJECTIVE: The aim of this study was to describe a comprehensive approach to decrease physical inactivity in the Veterans Health Administration (VHA) employee population. METHODS: The approach included (1) initiatives to decrease physical inactivity in the workplace; (2) two operational surveys to assess system-wide service provision; and (3) two national employee surveys. RESULTS: From 2010 to 2012, 86 employee fitness centers were completed in VA medical centers. A grants program (2010 to 2015) funded smaller projects designed to decrease physical inactivity in the workplace. Projects involved the provision of equipment to decrease sedentary behaviors, including stability balls, treadmill and sit-to-stand desks, stairwell projects, and funding for on-site fitness classes, bicycle racks, and outdoor par courses and walking paths among others. CONCLUSIONS: A comprehensive approach to decrease physical inactivity in VHA employees was successful. Overall, self-reported, age-adjusted physical inactivity in VHA employees decreased from 25.3% in 2010 to 16.1% in 2015.


Assuntos
Exercício Físico , Promoção da Saúde/métodos , Saúde Ocupacional , Saúde dos Veteranos , Humanos , Estados Unidos , United States Department of Veterans Affairs , Local de Trabalho
8.
J Occup Environ Med ; 58(5): 499-504, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27158957

RESUMO

OBJECTIVE: To conduct validation and dimensionality analyses for an existing measure of the integration of worksite health protection and health promotion approaches. METHODS: A survey of small to medium size employers located in the United States was conducted between October 2013 and March 2014 (N = 115). A survey of Department of Veterans Affairs (VA) administrative parents was also conducted from June to July 2014 (N = 140). Exploratory factor analysis (EFA) was used to determine the dimensionality of the Integration Score in each sample. RESULTS: Using EFA, both samples indicated the presence of one unified factor. The VA survey indicated that customization improves the relevance of the Integration Score for different types of organizations. CONCLUSIONS: The Integration Score is a valid index for assessing the integration of worksite health protection and health promotion approaches and is customizable based on industry. CLINICAL SIGNIFICANCE: The Integration Score may be used as a single metric for assessing the integration of worksite health protection and health promotion approaches in differing work contexts.


Assuntos
Promoção da Saúde , Serviços de Saúde do Trabalhador , Local de Trabalho , Empresa de Pequeno Porte , Inquéritos e Questionários , Estados Unidos , United States Department of Veterans Affairs
9.
J Occup Environ Med ; 58(5): 525-31, 2016 05.
Artigo em Inglês | MEDLINE | ID: mdl-27158961

RESUMO

OBJECTIVE: To describe a comprehensive approach to increase tobacco use cessation in the Veterans Health Administration (VHA) employee population. METHODS: The approach included: 1) national policy; 2) a pilot tobacco use cessation program; and 3) two operational surveys to assess system-wide tobacco use cessation service provision. RESULTS: The proportion of VHA facilities offering a comprehensive tobacco use cessation program increased from 51% in 2010 to 72% in 2014, with 83% of facilities providing nicotine replacement therapy to employees. The WIN by Quitting Tobacco program was successful; employees who participated in the pilot program quit tobacco at high rates (64% at 1 month post quit date). CONCLUSIONS: From policy to practice, the comprehensive approach to tobacco use cessation in VHA was successful and may serve as a model for future workplace health promotion and occupational safety and health initiatives.


Assuntos
Serviços de Saúde do Trabalhador , Abandono do Hábito de Fumar , Abandono do Uso de Tabaco , Saúde dos Veteranos , Local de Trabalho , Política de Saúde , Promoção da Saúde , Humanos , Projetos Piloto , Inquéritos e Questionários , Estados Unidos , United States Department of Veterans Affairs
10.
J Occup Environ Med ; 55(3): 310-7, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23302701

RESUMO

OBJECTIVE: To determine whether a "worksite culture of health" exists within the Veterans Health Administration and implications on integrating employee health promotion programs. METHODS: Three national surveys were used-an organizational health survey, a health behaviors survey, and a worksite environment survey. Cross-sectional associations between measures of organizational health and employee health behaviors and between measures of organizational health and worksite environment were assessed. RESULTS: There were significant associations between a number of organizational health measures and a combined measure of health behaviors. Likewise, presence of employee-wellness committees and/or coaches was significantly associated with higher appraisal on organizational health measures. CONCLUSION: Results suggest that a worksite culture of health exists in some but not all facilities within Veterans Health Administration; this has implications for integrating employee health promotion programs systemwide. A phased-in approach is likely warranted.


Assuntos
Comportamentos Relacionados com a Saúde , Promoção da Saúde/organização & administração , Saúde Ocupacional/estatística & dados numéricos , United States Department of Veterans Affairs/organização & administração , Estudos Transversais , Política de Saúde , Promoção da Saúde/estatística & dados numéricos , Inquéritos Epidemiológicos , Humanos , Cultura Organizacional , Avaliação de Resultados em Cuidados de Saúde , Estados Unidos , United States Department of Veterans Affairs/estatística & dados numéricos
11.
J Occup Environ Hyg ; 10(2): 55-63, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23252582

RESUMO

Use of a stability ball alone and stability ball chair were evaluated in the Veterans Health Administration as possible alternatives to incorporate with regular office chair use. The evaluation of stability ball use was conducted under the auspices of a work site health promotion program as a cross-over trial with participants rotating through use of the stability ball, stability ball chair, and regular office chair on a monthly basis for a total duration of 3 months. Rotations on regular office chairs served as the control. Three medical facilities participated. A total of 193 employees completed a baseline questionnaire; 159 completed at least one post-rotation questionnaire. Self-reported measures included perceived posture when sitting, perceptions of overall balance, energy levels, job performance, safety, and pain. Use was associated with improvements in perceived posture (p < 0.0001) and energy levels (p = 0.007) for stability ball users compared with the office chair control, and improvements in perceived posture (p < 0.0001) and overall balance (p = 0.05) for stability ball chair users compared with the control. Use of stability balls at work decreases the likelihood of reporting pain from regular office chair use from approximately 45% to 21%. Alternatively, a high number of participants reported pain with use of the stability ball alone and stability ball chair, 42% and 45%, respectively. The perceived risks and benefits of stability ball use should be weighed when incorporating use.


Assuntos
Decoração de Interiores e Mobiliário , Postura , Local de Trabalho , Adolescente , Adulto , Fenômenos Biomecânicos , Ergonomia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Exposição Ocupacional , Dor
12.
Infect Control Hosp Epidemiol ; 33(9): 924-31, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22869267

RESUMO

OBJECTIVE: The main objectives of our study were to explore reasons for seasonal influenza vaccine acceptance and declination in employees of a large integrated healthcare system and to identify underlying constructs that influence acceptance versus declination. Secondary objectives were to determine whether vaccine acceptance varied by hospital location and to identify facility-level measures that explained variability. DESIGN: A national health promotion survey of employees was conducted that included items on vaccination in the 2009-2010 influenza season. The survey was administered with two other institutional surveys in a stratified fashion: approximately 40% of participating employees were randomly assigned to complete the health promotion survey. SETTING: National single-payer healthcare system with 152 hospitals. PARTICIPANTS: Employees of the healthcare system in 2010 who responded to the survey. METHODS: Factor analysis was used to identify underlying constructs that influenced vaccine acceptance versus declination. Mean factor scores were examined in relation to demographic characteristics and occupation. Multilevel logistic regression models were used to determine whether vaccine acceptance varied by location and to identify facility-level measures that explained variability. RESULTS: Four factors were identified related to vaccine declination and were labeled as (1) "don't care," (2) "don't want," (3) "don't believe," and (4) "don't know." Significant differences in mean factor scores existed by demographic characteristics and occupation. Vaccine acceptance varied by location, and vaccination rates in the previous year were an important facility-level predictor. CONCLUSIONS: Results should guide interventions that tailor messages on the basis of particular reasons for declination. Occupation-specific and culturally appropriate messaging should be considered. Continued efforts will be taken to better understand how workplace context influences vaccine acceptance.


Assuntos
Atitude do Pessoal de Saúde , Pessoal de Saúde/psicologia , Influenza Humana/prevenção & controle , Aceitação pelo Paciente de Cuidados de Saúde/psicologia , Vacinação/psicologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Análise Fatorial , Feminino , Pesquisas sobre Atenção à Saúde , Promoção da Saúde , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Recusa do Paciente ao Tratamento/psicologia , Estados Unidos
13.
J Occup Environ Med ; 53(10): 1134-45, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21926920

RESUMO

OBJECTIVE: To determine baseline prevalence of health behaviors and chronic health conditions in Veterans Health Administration (VHA) employees and highlight disparities by occupation group. METHODS: There were 29,834 responses to the survey. Age-standardized prevalence estimates for VHA employees were compared to national estimates from BRFSS surveys. The VHA estimates were analyzed for physicians and dentists; physician assistants and nurse practitioners; registered nurses; licensed practical nurses and nursing assistants; other clinical; nonclinical; and wage grade staff. Multilevel regression explored the effect of worksite. RESULTS: The VHA employees have higher rates of unhealthy behaviors and chronic health conditions than US adults, except for smoking. Results illustrated significant disparities between occupation groups by demographics and variability by worksite. CONCLUSIONS: Veterans Health Administration's population appears less healthy than the US general population. Disparities between occupation groups support the establishment of targeted health promotion programs, with attention paid to differences in local culture.


Assuntos
Comportamentos Relacionados com a Saúde , Pessoal de Saúde/estatística & dados numéricos , Promoção da Saúde , Disparidades nos Níveis de Saúde , Saúde Ocupacional , United States Department of Veterans Affairs/estatística & dados numéricos , Adulto , Artrite/epidemiologia , Asma/epidemiologia , Diabetes Mellitus Tipo 2/epidemiologia , Feminino , Comportamentos Relacionados com a Saúde/etnologia , Inquéritos Epidemiológicos , Humanos , Hipertensão/epidemiologia , Masculino , Pessoa de Meia-Idade , Estados Unidos/epidemiologia , Local de Trabalho , Adulto Jovem
14.
Disaster Med Public Health Prep ; 5 Suppl 2: S235-41, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21908701

RESUMO

OBJECTIVE: To determine relations between sick leave use and the 2009 novel influenza A (H1N1) influenza pandemic among clinical and nonclinical staff in the Veterans Health Administration (VHA). METHODS: Aggregate sick leave use for all VHA employees was monitored in near-real time during the 2009 H1N1 influenza pandemic and compared with historical data from 2004 to 2008. The ratio of sick leave use between clinical and nonclinical staff was examined. An autoregressive integrated moving average model was used to assess whether the pandemic had a significant effect on sick leave use. RESULTS: The H1N1 influenza pandemic was associated with a significant effect on sick leave use in the VHA during the second wave of the pandemic. During this wave, the ratio of clinical to nonclinical sick leave use changed; clinical staff began taking more leave than nonclinical staff for 3 successive 2-week pay periods, with ratio measures of 1.004, 1.018, and 1.011, respectively. Using an autoregressive integrated moving average model with a pulse variable representing the pandemic, there was a significant effect on sick leave use. The average hours of sick leave used per full-time equivalent staff member per month increased by 0.3904 hours (P = .003) for clinical staff and 0.3898 hours (P = .01) for nonclinical staff over previous months during the first month of the second pandemic wave. CONCLUSIONS: Work loss associated with a pandemic is an important indicator of disease activity and may be a more sensitive indicator of emerging strains than deaths. Monitoring sick leave use in near real time in a large national health care system may be an important early indicator of pandemic severity with practical implications that should be considered in addition to more traditional measures of influenza epidemic and pandemic severity.


Assuntos
Vírus da Influenza A Subtipo H1N1 , Influenza Humana , Saúde Ocupacional , Pandemias , Vigilância da População , Licença Médica/estatística & dados numéricos , United States Department of Veterans Affairs , Humanos , Vigilância da População/métodos , Estados Unidos
15.
Am J Respir Crit Care Med ; 182(7): 890-6, 2010 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-20075385

RESUMO

RATIONALE: The effect of disease management for chronic obstructive pulmonary disease (COPD) is not well established. OBJECTIVES: To determine whether a simplified disease management program reduces hospital admissions and emergency department (ED) visits due to COPD. METHODS: We performed a randomized, adjudicator-blinded, controlled, 1-year trial at five Veterans Affairs medical centers of 743 patients with severe COPD and one or more of the following during the previous year: hospital admission or ED visit for COPD, chronic home oxygen use, or course of systemic corticosteroids for COPD. Control group patients received usual care. Intervention group patients received a single 1- to 1.5-hour education session, an action plan for self-treatment of exacerbations, and monthly follow-up calls from a case manager. MEASUREMENTS AND MAIN RESULTS: We determined the combined number of COPD-related hospitalizations and ED visits per patient. Secondary outcomes included hospitalizations and ED visits for all causes, respiratory medication use, mortality, and change in Saint George's Respiratory Questionnaire. After 1 year, the mean cumulative frequency of COPD-related hospitalizations and ED visits was 0.82 per patient in usual care and 0.48 per patient in disease management (difference, 0.34; 95% confidence interval, 0.15-0.52; P < 0.001). Disease management reduced hospitalizations for cardiac or pulmonary conditions other than COPD by 49%, hospitalizations for all causes by 28%, and ED visits for all causes by 27% (P < 0.05 for all). CONCLUSIONS: A relatively simple disease management program reduced hospitalizations and ED visits for COPD. Clinical trial registered with www.clinicaltrials.gov (NCT00126776).


Assuntos
Gerenciamento Clínico , Educação de Pacientes como Assunto , Doença Pulmonar Obstrutiva Crônica/terapia , Autocuidado , Idoso , Feminino , Serviços de Saúde/estatística & dados numéricos , Humanos , Masculino , Admissão do Paciente/estatística & dados numéricos , Método Simples-Cego , Análise de Sobrevida , Veteranos/estatística & dados numéricos
16.
J Occup Environ Med ; 48(6): 541-8, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16766917

RESUMO

According to Healthy People 2010, 95% of employers with more than 50 employees reported that they offered at least one health promotion activity by 1999. Employment-based health promotion/disease prevention (hp/dp) programs have significantly increased in frequency and scope since 1985. Yet, 20 years later, the reported results for employee health lag behind the literature documenting the impact of lifestyle-related health risks on morbidity, healthcare utilization, and costs. In this article, we consider the key stakeholders involved-employers, health plans, and employees-and explore their legitimate and feasible roles in employment-based hp/dp programs, including the incentives and barriers they face to program participation. We argue for the integration of hp/dp programs into the traditional health protection mission of occupational health and safety professionals.


Assuntos
Promoção da Saúde/organização & administração , Serviços de Saúde do Trabalhador/organização & administração , Gerenciamento Clínico , Health Insurance Portability and Accountability Act , Humanos , Estilo de Vida , Cultura Organizacional , Estados Unidos
17.
Maturitas ; 48(3): 209-18, 2004 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-15207886

RESUMO

OBJECTIVES: The purpose of this analysis was to compare the effects of two dietary supplements derived from red clover to placebo on lipids and bone turnover markers in symptomatic menopausal women. METHODS: The study was a 12-week randomized, double-blind, placebo-controlled trial. Two hundred and fifty-two menopausal women ages 45-60 years experiencing > or =35 hot flashes per week were randomly assigned to Promensil (82 mg total isoflavones), Rimostil (57.2 mg total isoflavones), or placebo. Primary outcome measures were mean absolute changes for HDL-cholesterol, serum osteocalcin, and urinary N-telopeptide. Secondary outcome measures were mean changes of total cholesterol, LDL-cholesterol, the ratio of HDL- to LDL-cholesterol, and triglycerides. RESULTS: Ninety-eight percent of participants completed the 12-week protocol. Women taking Rimostil or Promensil compared to those taking placebo had greater mean increases in HDL-cholesterol; however, this change was small in magnitude (<2 mg/dl) and did not reach significance. There was a significant decrease in triglyceride levels among women taking Rimostil (14.4 mg/dl, P = 0.02) or Promensil (10.9 mg/dl, P = 0.05) compared to those taking placebo. The decrease was primarily among women with elevated baseline triglyceride levels (P for interaction = 0.009). There were no differences in mean changes of total cholesterol, LDL-cholesterol, or the ratio of HDL- to LDL-cholesterol among treatment groups. There were no statistically significant differences among treatment groups for bone turnover markers. CONCLUSIONS: Compared with placebo, both of the supplements containing isoflavones decrease levels of triglycerides in symptomatic menopausal women; however, this effect is small in magnitude.


Assuntos
Osso e Ossos/metabolismo , Doenças Cardiovasculares/prevenção & controle , Fogachos/tratamento farmacológico , Isoflavonas/uso terapêutico , Lipídeos/sangue , Osteoporose Pós-Menopausa/prevenção & controle , Osso e Ossos/efeitos dos fármacos , Colágeno/urina , Colágeno Tipo I , Suplementos Nutricionais , Feminino , Seguimentos , Humanos , Isoflavonas/farmacologia , Menopausa/efeitos dos fármacos , Pessoa de Meia-Idade , Osteocalcina/sangue , Peptídeos/urina , Extratos Vegetais/uso terapêutico , Resultado do Tratamento , Triglicerídeos/sangue
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