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J Craniomaxillofac Surg ; 47(3): 484-490, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30661927

RESUMO

PURPOSE: Successful implant therapy is based on fast, safe, and predictable osseointegration. Several surface modifications have been introduced to improve the bone-to-implant interaction. This in vivo study evaluates the impact of plasma surface conditioning on early wound healing and osseointegration. MATERIALS AND METHODS: A total of 16 dental implants with a sand-blasted and acid-etched surface were conditioned with cold atmospheric plasma prior to insertion in the frontal bone of four miniature pigs. Sequential fluorescence labeling was administered to label bone metabolism, and after 8 weeks, bone blocks were harvested for radiological, histological, and histomorphometrical evaluation. RESULTS: The plasma conditioning had no impact on the morphology of the implant surface. The bone-to-implant contact ratio was 90.4% and 86.5%, the interthread bone density 72.5% and 63.4%, and the periimplant bone density 60.5% and 61.1%, in the plasma conditioned group and control group, respectively. Concentric bands of fluorescence enrichment indicated a chronological and homogenous mineralization of newly formed bone. No unwanted periimplant side effects were detected. CONCLUSION: The increased parameters for osseointegration in this in vivo study merit further investigation in prospective clinical trials.


Assuntos
Argônio , Implantação Dentária Endóssea , Implantes Dentários , Osseointegração , Titânio , Cicatrização , Condicionamento Ácido do Dente , Animais , Densidade Óssea , Planejamento de Prótese Dentária , Microscopia Eletrônica de Varredura , Microscopia de Fluorescência , Modelos Animais , Gases em Plasma , Propriedades de Superfície , Suínos , Porco Miniatura
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