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Graefes Arch Clin Exp Ophthalmol ; 248(9): 1331-7, 2010 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-20464557

RESUMO

PURPOSE: To investigate fixation pattern and retinal sensitivity in patients with serpiginous choroiditis (SC). METHODS: Twenty-eight eyes (14 patients) with SC were evaluated. Best-corrected visual acuity, color fundus photography, fundus autofluorescence, and fluorescein and indocyanine green angiography were performed. Microperimetry was used to assess fixation pattern and retinal sensitivity. RESULTS: Of 28 eyes, 16 (57%) had central, one (4%) poor central, and 11 (39%) eccentric fixation; and 18 (64%) had stable, four (14%) relatively unstable, and six (21%) unstable fixation. In patients with posterior pole symmetrically involved in both eyes, the better eye had stable and central fixation in all cases. Atrophic lesions were characterized by a dense scotoma in all cases, with a relative scotoma at their margins in ten eyes (38%). In two cases of active disease, a dense scotoma correlated to an active lesion could be detected. A relative scotoma was documented in areas not involved by the disease at the posterior pole in eight eyes (28%), and in the peripapillary area in 11 eyes (39%). CONCLUSIONS: Quantification of retinal sensitivity and fixation pattern by microperimetry offers new data about the impact of visual impairment in patients with SC. A reduction of retinal sensitivity in an apparently healthy area suggests a wider functional involvement of the retina, undetectable by morphologic evaluation alone.


Assuntos
Corioidite/fisiopatologia , Retina/fisiopatologia , Testes de Campo Visual , Corioidite/diagnóstico , Corantes , Fixação Ocular/fisiologia , Angiofluoresceinografia , Humanos , Verde de Indocianina , Masculino , Pessoa de Meia-Idade , Escotoma/diagnóstico , Escotoma/fisiopatologia , Acuidade Visual/fisiologia
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