RESUMO
Luego del brote de COVID-19 en el mundo, en medio de una crisis sanitaria, la odontología como profesión de alto nivel de riesgo de contaminación se plantea un reto, para la restructuración de sus procedimientos. Al respecto, se han revisado diferentes enfoques de las guías internacionales con diferentes realidades y experiencias en el campo, llegando a recomendaciones para el diseño y uso del óptimo equipo de protección personal (EPP) en tiempos de escasez, minimizando los riesgos de contaminación. Sin embargo, la mayor parte de estas no están apoyadas con evidencia científica odontológica, mientras que se van desarrollando nuevos dispositivos, minimizando la exposición a procedimientos generadores de aerosoles (PGA) como barreras físicas.
After the outbreak of COVID-19 in the world, during a health crisis, dentistry as a profession with a high level of risk of contamination poses a challenge, for the restructuring of its procedures. In this regard, different approaches to international guidelines have been reviewed with diverse realities and experiences in the field, reaching recommendations for the design and use of optimal personal protective equipment (PPE) in times of scarcity, minimizing the risks of contamination. However, most of these are not supported by dental scientific evidence, while new devices are being developed, minimizing exposure to aerosol-generating procedures (PGA) as physical barriers.
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AIM: The aim was to evaluate and compare the therapeutic effect of sodium hyaluronate (SH) and corticosteroids (CS) on pain and temporomandibular dysfunction (TMD). MATERIALS AND METHODS: Thirty patients with TMD [characterized by painful symptoms, affectations, and limitations of the mandibular movement and noises or clicks in the temporomandibular joint (TMJ)] were selected and divided into two equal groups nonrandomized. The clinical questionnaire was applied to each patient before performing the clinical procedures and included a visual analog scale with progressive values from 0 to 10 for the measurement of pain and clinical examination: maximum oral aperture (MOA), mandibular laterotrusive movement (MLM), and maximum protrusion (MP), before and after infiltration intra-articular with SH and CS up to 2 months. RESULTS: Both groups described benefits from treatment at the 1st and 2nd weeks, and at 1 and 2 months of follow-up, presenting a reduction in TMJ pain, and improvement in mandibular mobility with an increase of the MOA, lateralities, and protrusion. No statistically significant difference was found among these variables between the two drugs. However, SH showed a greater therapeutic effect in relation to a reduction in joint noises compared to CS. CONCLUSION: Intra-articular infiltration with SH and CS in TMD is effective for the relief of TMJ pain and also reduces joint noises and improves mandibular mobility. Both drugs can be used with similar optimal results in the treatment of TMD. CLINICAL SIGNIFICANCE: This research allows to know what is the therapeutic impact of injectable CS on the TMJ.
Assuntos
Ácido Hialurônico , Transtornos da Articulação Temporomandibular , Corticosteroides , Humanos , Dor , Articulação Temporomandibular , Transtornos da Articulação Temporomandibular/tratamento farmacológicoRESUMO
AIM: "Tocosh" is a potato that has undergone a process of hydraulic oxidation that enhances its antimicrobial properties so that this natural resource can be used in medical sciences. The aim of this study was to develop and evaluate the antibacterial and cytotoxic activity of a new experimental tooth based on Solanum tuberosum "Tocosh" on the cell lines 3T3 and DU145. MATERIALS AND METHODS: To evaluate the cytotoxicity, cell cultures 3T3 and DU145 were used. Cell viability was determined by the MTT assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) in a medium containing 10% calf serum where the cells were preincubated at a concentration of 1 × 106 cells/mL in culture medium for 3 hours at 37°C and 6.5% CO2. Then, the absorbance was measured using a microplate reader where the formazan crystals were diluted with acidic and cold isopropanol, and quantified in an ELISA reader. To evaluate the antibacterial effect, the Kirby Bauer inhibition halos method was used on strains of S. aureus (ATCC 25923), S. mutans (ATCC 25175), and S. mitis (ATCC 49456). RESULTS: Solanum tuberosum (tocosh) was not cytotoxic because it only had one CC50 at the concentration of 0.26927 mg/mL and 0.26845 mg/mL for the cell lines 3T3 and DU145, respectively. Tocosh toothpaste (TD) has an antibacterial effect against S. aureus and S. mutans. CONCLUSION: The new ecological dentifrice was not cytotoxic since it did not alter cell viability because its CC50 was only 0.268 and 0.269 µg/mL for the 3T3 and DU145 cell lines, respectively; however, it presented an optimal antimicrobial activity against the oral strains evaluated. CLINICAL SIGNIFICANCE: This research has great potential for clinical use because this new dentifrice has antimicrobial activity against different oral germs. How to cite this article: Mayta-Tovalino F, Sedano-Balbin G, Romero-Tapia P, et al. Development of New Experimental Dentifrice of Peruvian Solanum tuberosum (Tocosh) Fermented by Water Stress: Antibacterial and Cytotoxic Activity. J Contemp Dent Pract 2019;20(10):1206-1211.
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Dentifrícios , Solanum tuberosum , Antibacterianos , Desidratação , Humanos , Testes de Sensibilidade Microbiana , Peru , Staphylococcus aureus , Cremes DentaisRESUMO
AIM: The aim of this study is to assess the epidemiological profile of 12- to 16-year-old adolescents with Down syndrome in the Special Basic Education Center in Lima-Peru. MATERIALS AND METHODS: A cross-sectional descriptive study was performed, where the epidemiological profile was determined through the DMF-T index, oral hygiene index (OHI), and the gingival index from Silness and Löe. A sample of 107 adolescents with Down syndrome in a Peruvian rural population were considered who were evaluated with the formula of proportion estimation, of which 48 (44.8%) were females and 55 (59%) males. RESULTS: Patients with mild to moderate Down syndrome were with a caries prevalence of 42 and 27.1%, respectively. Likewise, class III malocclusion was present in 42.9 and 25.2%. The most prevalent OHI was the regular category with 66.2%. RESULTS: Patients with mild to moderate Down syndrome were with a caries prevalence of 42 and 27.1%, respectively. Likewise, class III malocclusion was present in 42.9 and 25.2%. The most prevalent OHI was the regular category with 66.2%. CONCLUSION: It was evident in mild Down syndrome adolescents, a higher prevalence of the indexes: dental caries, malocclusion, periodontal disease, and oral hygiene, moderate to severe.
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Cárie Dentária , Síndrome de Down , Adolescente , Criança , Estudos Transversais , Índice CPO , Feminino , Humanos , Masculino , Peru , Prevalência , Fatores de Risco , População RuralRESUMO
La Hiperplasia condilar (HC) fue descrita inicialmente por Robert Adams en 1836. Esta patología mandibular presenta varios tipos que afectan el tamaño y la morfología ósea, alteran la oclusión y las estructuras dentolabiales, afectan indirectamente al maxilar superior, dando como resultado patrones faciales que se pueden caracterizar por: prognatismo mandibular, aumento unilateral del cóndilo, el cuello, la rama y el cuerpo, asimetría facial, disfunción de la articulación temporomandibular, desequilibrio neuromuscular y patología dolorosa miofacial. Esta condición de la HC, hace que requiera de un trata-miento multidisciplinario, que seguÌn su severidad, compete a cirujanos bucomaxilofaciales, ortodoncistas, fisioterapeutas y cirujanos plaÌsticos. El diagnóstico de la HC se basa en la anamnesis, el examen clínico y la evaluación imagenológica, consistente en radiografías panoraÌmica cefalométrica, tomografía macizo facial (TEM-CBCT), gammagrafía ósea y en algunos casos estudio anaÌtomo-patológico. El propósito de esta revisión es conocer de manera detallada el comportamiento y pronóstico de esta patología de acuerdo al tipo, con la finalidad de facilitar el diagnóstico y las opciones terapéuticas, seguÌn la severidad, la edad del paciente y la patología en su forma activa o inactiva. Palabras clave: Asimetría facial; Cóndilo mandibular; Prognatismo; Anomalías maxilo-faciales; Tomografía; Cirugía ortognaÌtica.
Condylar hyperplasia (HC) was first described by Robert Adams in 1836. This mandibular pathology presents several types that affect bone size and morphology, alter occlusion and dentolabial structures, indirectly affect the maxilla, resulting in facial patterns that can be characterized by: mandibular prognathism, unilateral increase of the condyle, neck, branch and body, facial asymmetry, temporomandibular joint dysfunction, neuro-muscular imbalance and myofacial pain pathology. This condition of the HC, requires a multidisciplinary treatment, which according to its severity, is the responsibility of oral and maxillofacial surgeons, orthodontists, physiotherapists, plastic surgeons. The diagnosis of HC is based on the anamnesis, the clinical examination and the imaging evaluation, consisting of panoramic cephalometric radiographs, macizo-facial tomography (TEM-CBCT), bone scintigraphy and in some cases anatomo-pathological study. The purpose of this review is to know in detail the behavior and prognosis of this pathology according to the type, in order to facilitate diagnosis and therapeutic options, according to the severity, the age of the patient and the pathology in its active form or inactive. Keywords: Facial asymmetry; Mandibular condyle; Prognathism; Maxillofacial abnormalities; Tomography; Orthognathic surgery.
