RESUMO
The results of examinations of 66 newborns were used to suggest a new approach for evaluating the curves of medium urea molecules (calculations of the relative area beneath the curve and of areas of the first and second maxima). Issues related with the impact excreted by medication, endogenous intoxication and by a direct lesion to the renal tissues on a level of medium urea molecules are under discussion.
Assuntos
Doenças do Recém-Nascido/urina , Rim/fisiopatologia , Toxinas Biológicas/urina , Urinálise/métodos , Xenobióticos/urina , Humanos , Recém-Nascido , Doenças do Recém-Nascido/fisiopatologiaRESUMO
Serum hydrocortisone concentrations were measured by high performance liquid chromatography (HPLC) and radioimmunoassay (RIA) in 24 children with different diseases and 16 healthy adults. HPLC and RIA proved to be equally sensitive. However the authors recommend HPLC as a reliable, rapid, and ecologically pure method, which is, in addition, selective and economic.