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3.
Semin Thromb Hemost ; 12(3): 181-3, 1986 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-3775386

RESUMO

During the clotting of blood, prothrombin is virtually all converted to thrombin. By contrast, Factor X is not. Large quantities of thrombin are inhibited by plasma and platelet AT III (heparin cofactor I), by heparin cofactor II, and by fibrin. Lesser quantities function in various reactions in which thrombin specificity is modified for greater effectiveness. Some thrombin binds to platelets as well as blood vessel endothelial cells, but the latter facts were not included herein.


Assuntos
Coagulação Sanguínea , Trombina/metabolismo , Animais , Antitrombina III/metabolismo , Fator X/metabolismo , Glicoproteínas/metabolismo , Cofator II da Heparina , Humanos , Protrombina/metabolismo
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