On the Biopsychosocial Costs of Alienated Labor.

Data from the national, longitudinal Mid-Life in the US (MIDUS) study were used to examine work alienation and its relationship to biological health as well as psychological and social functioning. The alienation measure focuses on the autonomy and creativity the work provides. We hypothesized that alienated work would have negative associations with each of the three domains: in biology, higher 'allostatic load' (biological dysregulation); in psychology, poorer cognitive performance; and socially, negative impacts on family life. The outcomes are generally as predicted, though there are notable differences for men and women.

Social status and biological dysregulation: the "status syndrome" and allostatic load.

Data from a national sample of 1255 adults who were part of the MIDUS (Mid-life in the U.S.) follow-up study and agreed to participate in a clinic-based in-depth assessment of their health status were used to test the hypothesis that, quite part from income or educational status, perceptions of lower achieved rank relative to others and of relative inequality in key life domains would be associated with greater evidence of biological health risks (i.e., higher allostatic load). Results indicate that over a variety of status indices (including, for example, the person's sense of control, placement in the community rank hierarchy, perception of inequality in the workplace) a syndrome of perceived relative deprivation is associated with higher levels of biological dysregulation. The evidence is interpreted in light of the well-established associations between lower socio-economic status and various clinically identified health morbidities. The present evidence serves, in effect, both as a part of the explanation of how socio-economic disparities produce downstream morbidity, and as an early warning system regarding the ultimate health effects of currently increasing status inequalities.

Late life cognition among men: a life course perspective on psychosocial experience.

This report assesses associations between trajectories of psychosocial experience over the life course and cognitive function in late life men. Survey data from the National Longitudinal Study of Older Men, a community sample of 1835 United States men aged 45-59 years in 1966, are used to explore the cognitive effects of personality (locus of control) and emotion (affect) as these attributes evolve from middle age to late life. Locus of control is very stable over time, whereas negative and positive affect fluctuate. Inverse relationships are found between cognitive function and external locus of control, enduring negative affect, and the absence of positive affect. Levels of education also moderate these effects. Low educational attainment appears to intensify the risk for poor cognitive function associated with mixed internal-external locus of control and poor emotional state over time. The connection between education, usually completed early in the life course, and late life cognitive outcomes emphasizes the importance of promoting educational attainment among young people. Among older men with low educational attainment, the identification of mood disorders and personality attributes that negatively impact cognition may lead to the development of appropriate interventions.

Religiosity/spirituality and health. A critical review of the evidence for biological pathways.

The authors review evidence regarding the biological processes that may link religiosity/spirituality to health. A growing body of observational evidence supports the hypothesis that links religiosity/spirituality to physiological processes. Although much of the earliest evidence came from cross-sectional studies with questionable generalizability and potential confounding, more recent research, with more representative samples and multivariate analysis, provides stronger evidence linking Judeo-Christian religious practices to blood pressure and immune function. The strongest evidence comes from randomized interventional trials reporting the beneficial physiological impact of meditation (primarily transcendental meditation). Overall, available evidence is generally consistent with the hypothesis that religiosity/spirituality is linked to health-related physiological processes--including cardiovascular, neuroendocrine, and immune function--althogh more solid evidence is needed.