[Evaluation of functional capacity]. / Evaluation de la capacité fonctionnelle.

A functional capacity evaluation (FCE) is a detailed examination and evaluation that objectively measures the individual's current level of safe functional abilities, primarily within the context of the demands of competitive employment. It measures the ability to perform functional or work-related tasks and predicts the potential to sustain these tasks over a defined time-frame. Measurements of function from an FCE are compared to the physical demands of a job or other functional activities, and are used to make return-to-work/activity decisions, disability determinations, or to generate a rehabilitation plan. Scientific evidence on validity and reliability is limited so far. An FCE is time-consuming and cannot be recommended as a routine evaluation.

The effects of the beta-adrenoceptor blocking agent LL 21-945 on renal hypertensive (Grollman) rats.

Prophylactic administration of LL 21-945 [4-(3-tert. butyl-amino-2-pivaloyloxypropoxy)-9-fluorenone] during 15 weeks to Grollman rats depressed the development of hypertension, tachycardia and myocardial pathogical changes. The tachycardia was eliminated and the degree of the myocardial pathological changes and coronary sclerosis was less severe than in the untreated Grollman rats. The survival rate was slightly improved with LL 21-945. With respect to the biochemical parameters studied, only a tendency of LL 21-945 to moderate the rises in blood cholesterol, total glycerides and urea was observed towards the end of the experiment.