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1.
Adv Exp Med Biol ; 1425: 161-169, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37581790

RESUMO

Children whose parents are diagnosed with alcohol use problems are exposed to genetic and environmental risk factors and face a greater risk of developing mental health and behavioral problems and a higher risk of alcohol use. In this study, we present the case of a father and his son, both diagnosed with alcohol use disorder, who both attended, 12 years apart, the Inpatient Alcohol Treatment Program of the Alcohol Treatment Unit, in the Psychiatric Hospital of Attica, in Athens. The Alcohol Treatment Unit offers two inpatient treatment programs that have been operating since 1996 and are based on the principles of the Therapeutic Community. It was the first time that both a father and son coming from the same family attended one of these programs. The aim of this study is to extract useful information regarding the dynamics of a family in which alcohol dependence is transferred from generation to generation. Therapists try to decode this transference and interpret attitudes and behaviors under these circumstances.


Assuntos
Alcoolismo , Humanos , Masculino , Consumo de Bebidas Alcoólicas/efeitos adversos , Pai/psicologia , Alcoolismo/terapia , Planejamento em Saúde
2.
In Vivo ; 36(5): 2092-2104, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36099111

RESUMO

BACKGROUND/AIM: Alcohol use disorder (AUD) is a chronic, multifactorial psychiatric condition with an enormous impact on public health and social cost. Genetic studies suggest a heritability, and genome-wide association studies (GWAS) have revealed genetic polymorphisms influencing AUD development. Our study aimed to investigate known variants located in ADH1B, DRD2, FAAH, SLC39A8, GCKR, and PDYN genes (rs1229984, rs7121986, rs324420, rs13107325, rs1260326, rs2281285 respectively) in an AUD Greek cohort in order to shed more light on the genetic predisposition to AUD. MATERIALS AND METHODS: Alcohol-dependent individuals (n=251) meeting both the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) and the ICD-10 guidelines for alcohol abuse and dependence, and control individuals (n=280) were recruited. DNA was extracted from whole blood and PCR-restriction fragment length polymorphism (RFLP-PCR) or allele-specific PCR method was used for genotyping. RESULTS: Individuals carrying the FAAH rs324420 A allele were significantly associated with increased risk of AUD (p<0.0001). SLC39A8 rs13107325 T allele and ADH1B rs1229984 T allele are overrepresented in control subjects (p<0.0001 and p<0.0001, respectively). The associations are maintained following an adjustment for age and sex and Bonferroni correction. GCKR rs13107325, DRD2 rs7121986, and PDYN rs2281285 polymorphisms did not show a significant association with AUD in the studied population after Bonferroni correction. CONCLUSION: Susceptibility to AUD is related to variations in FAAH, ADH1B, and SLC39A8 genes. These polymorphisms could serve as potential biomarkers for AUD risk.


Assuntos
Alcoolismo , Proteínas Adaptadoras de Transdução de Sinal/genética , Álcool Desidrogenase/genética , Alcoolismo/diagnóstico , Alcoolismo/genética , Estudo de Associação Genômica Ampla , Humanos , Polimorfismo de Nucleotídeo Único , Receptores de Dopamina D2/genética
3.
BMC Psychiatry ; 22(1): 2, 2022 01 04.
Artigo em Inglês | MEDLINE | ID: mdl-34983447

RESUMO

BACKGROUND: There is an increasing trend of door locking practices in acute psychiatric care. The aim of the present study was to illuminate the symbolic dimensions of doors in Greek mental health nurses' experiences of open and locked working spaces. RESULTS: A sequential mixed-method designexplored the experiences of nurses working in both open and locked psychiatric acute care units. Participants experiences revealed four types of doors related to the quality of recovery-oriented care: (a) the open door, (b) the invisible door, (c) the restraining door, and (d) the revolving door. Open doors and permeable spacesgenerated trust and facilitated the diffusion of tension and the necessary perception of feeling safe in order to be involved in therapeutic engagement. When the locked unit was experienced as a caring environment, the locked doors appeared to be "invisible". The restraining doors symbolized loss of control, social distance and stigma echoing the consequences of restrictingpeople's crucial control over spaceduring the COVID-19 pandemicin relation toviolence within families, groups and communities. The revolving door (service users' abscondence/re-admission) symbolised the rejection of the offered therapeutic environment and was a source of indignation and compassion fatigue in both open and locked spaces attributed to internal structural acute care characteristics (limited staffing levels, support, resources and activities for service users) as well as 'locked doors' in the community (limited or no care continuity and stigma). CONCLUSIONS: The impact of COVID-19 restrictions on people's crucial control of space provides an impetus for erecting barriers masked by the veil of habit and reconsidering the impact of the simple act of leaving the door open/locked to allow both psychiatric acute care unit staff and service users to reach their potential.


Assuntos
COVID-19 , Transtornos Mentais , Grécia , Humanos , Transtornos Mentais/terapia , Psicoterapia , SARS-CoV-2
4.
J Addict Nurs ; 32(4): 225-234, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34855321

RESUMO

ABSTRACT: The risk of compassion fatigue (CF) for professionals who support and care for individuals and families facing the dual burden of addiction and trauma has been recently recognized. The aim of this mixed methods study was to investigate CF/secondary traumatic stress and compassion satisfaction (CS) in addiction nursing care providers. The Professional Quality of Life Scale was distributed to 21 addiction nurses and 29 nurse assistants in the alcohol and drug dependency centers of a psychiatric hospital in Greece. High CF risk was reported in 22% of participants, whereas 46% expressed high-to-moderate potential for CS. Participants described the long transition from compassion frustration or disengagement at the beginning of their career to CS at later stages. Learning to be compassionate entailed finding the right distance, redefining therapeutic role and expectations, and containing feelings and experiences. Being able to experience CS involved getting satisfaction from small changes, personal and professional growth, and self-care. A compassionate organizational culture, clinical supervision, and ongoing education may protect addiction professionals from absorbing or internalizing unmanageable emotions, which may lead to CF and also help them to gain a deeper understanding of their communication and interactions with individuals fighting addiction.


Assuntos
Esgotamento Profissional , Fadiga de Compaixão , Estudos Transversais , Empatia , Grécia , Humanos , Satisfação Pessoal , Qualidade de Vida , Inquéritos e Questionários
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