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1.
Eksp Klin Farmakol ; 70(5): 44-6, 2007.
Artigo em Russo | MEDLINE | ID: mdl-18074807

RESUMO

The effects of a submaximum single physical load with a mixed aerobic-anaerobic character (combined rowing test) on the intensity of lipid peroxidation (LPO) processes, antioxidant state of the organism, and rheological properties of blood have been studied in a group of athletes. The administration of natural antioxidants significantly decreased the LPO stress induced by the physical load, reduced the suppression of the antioxidant system of the organism, and normalized the LPO-disturbed hemorheological parameters. Antioxidants such as carnosine, cytamine, and apilac can be used as non-doping means for the accelerated recovery and increase in the physical work capacity in athletes.


Assuntos
Antioxidantes/uso terapêutico , Produtos Biológicos/uso terapêutico , Carnosina/uso terapêutico , Exercício Físico/fisiologia , Estresse Oxidativo/efeitos dos fármacos , Adolescente , Adulto , Humanos , Esportes
2.
Eksp Klin Farmakol ; 68(5): 44-6, 2005.
Artigo em Russo | MEDLINE | ID: mdl-16277211

RESUMO

The effects of carnosine and its combination with essentiale on the processes of lipid peroxidation (LPO) and on the work capacity have been studied in mice. The administration of camosine, essentiale, and vitamin E, increased the work capacity of laboratory mice to a different extent, the effect being most pronounced for a mixture of carnosine and essentiale. Carnosine in the dose range studied exhibited a pronounced antioxidant effect with respect to LPO and optimized the potential of the organism in the course of intensive physical activity. This drug is not a doping and can be recommended as a means of improvement of the physical capacity.


Assuntos
Antioxidantes/farmacologia , Carnosina/farmacologia , Peroxidação de Lipídeos/efeitos dos fármacos , Atividade Motora/efeitos dos fármacos , Fosfatidilcolinas/farmacologia , Animais , Camundongos , Camundongos Endogâmicos , Natação
3.
Eksp Klin Farmakol ; 67(3): 66-8, 2004.
Artigo em Russo | MEDLINE | ID: mdl-15341074

RESUMO

Cytamines (hepatamin, epifamin, and suprenamin) administered in various combinations increase the working ability of high-rank athletes in experiments. These cytamines also potentiate the effects of apilak, ecdystene, vitamax, and essentiale preparations on the exercise tolerance.


Assuntos
Produtos Biológicos/farmacologia , Exercício Físico , Nucleoproteínas/farmacologia , Fosfatidilcolinas/farmacologia , Esportes , Esteroides/farmacologia , Interações Medicamentosas , Ergometria , Humanos
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