RESUMO
AIM: To introduce the pancreatic index assessing severity of chronic pancreatitis (CP). MATERIAL AND METHODS: Ultrasonography was made in 28 patients with clinically documented diagnosis of CP. A total of 6 groups of ultrasonographic signs served the basis for calculation of scores for a complex formalized semiquantitative criterion--the pancreatic index (PI). Ultrasonographic signs--the size of the head, calcinates, structure, maximal size of the ductus pancreaticus, pseudocysts, etc. were assessed in scores from 1 to 3. Severity of the disease was classified according to total PI. RESULTS: The following correlation was found between severity of CP and the PI: in mild CP--57%, in moderate CP--71%, in severe CP--66%. CONCLUSION: Ultrasonographic PI objectively evaluates severity of CP course.
Assuntos
Pancreatite/diagnóstico por imagem , Pancreatite/fisiopatologia , Doença Crônica , Progressão da Doença , Humanos , Pseudocisto Pancreático/diagnóstico por imagem , Pseudocisto Pancreático/fisiopatologia , Tomografia Computadorizada por Raios X , UltrassonografiaRESUMO
Duodenal bile taken by gastroduodenal intubation of patients with chronic calculous cholecystitis with intact gallbladder performance was investigated as was the bile taken in those with chronic acalculous cholecystitis or in those without clinical signs of cholecystitis and concurrent diseases. The bile was investigated for cholesterol, bile acids and lecithin levels. All the parameters obtained were used for computation of lithogeny parameters: Swell, Admirand-Small, Metzger, Thomas, Andrews and cholesterol-lecithin ratio. The study performed indicated that Swell's parameters of lithogeny and cholesterol-lecithin ratio displayed more precisely lithogeny of the bile, and could be determined more easily than other parameters.
Assuntos
Bile/metabolismo , Colelitíase/etiologia , Colesterol/metabolismo , Duodeno/metabolismo , Ácidos Graxos/metabolismo , Fosfatidilcolinas/metabolismo , Bile/química , Colelitíase/química , Colelitíase/diagnóstico , Colesterol/química , Doença Crônica , Ácidos Graxos/química , Humanos , Fosfatidilcolinas/química , Valores de ReferênciaAssuntos
Medicina Aeroespacial/métodos , Cromossomos Humanos Par 16/química , Cromossomos Humanos Par 1/química , Cromossomos Humanos Par 9/química , Heterocromatina/química , Linfócitos/ultraestrutura , Cromossomo Y/química , Células Cultivadas , Humanos , Linfócitos/química , Linfócitos/citologia , Metáfase , Coloração e Rotulagem/métodosRESUMO
The level of chromosome aberrations induced by mitomycin C and cytosine arabinoside in the cultured lymphocytes from patients with chronic alcoholism is elevated, as compared to that observed in the cultured lymphocytes of healthy persons. A supposition was made that transitory instability of cell genome could cause this phenomenon.
