[Effect of physical activity on spectral analysis indices of the heart rhythm in patients with stage II hypertension disease].

The authors aimed at studying wave structure of the heart rhythm of patients with II stage hypertension disease without and with physical activity. 72 patients with II stage hypertension disease (47 men and 33 women) have been observed. Investigators used national bicycle ergometer complex called VRR (Kiev, design office "Ergometr"). Indices of spectral analysis of the heart rhythm at rest and recovery period have been calculated. Bicycle ergometer diagnostic was carried out using continuously graduated increase of physical activity. Patients with II stage hypertension disease were found to have at rest the tendency to the increase of slow II grade waves and centralization index but indices of wave structure of heart rhythm at the period of recovery were not changed.

[Analysis of the questionnaire design in evaluation of patients with hypertensive disease].

The authors questionnaired 103 patients with hypertensive disease using 30 questions with simplified system of answers. The analysis showed that rural patients with hypertensive disease had their disease diagnosed during two years since the disease started only in 6% of cases. 36% of patients do not have an apparatus to measure blood pressure. 64% of hypertensive disease cases are diagnosed after patients present his/her complaints. Rural patients in 44.6% of cases received their treatment at home. In 74% of cases, patients consider that to be healthy they should receive antihypertensive therapy, but start the treatment in 61% of cases with raunatine and adelfane. Patients with hypertensive disease are rarely on beta-adrenoblockers (11.7%) and calcium antagonists (9.7%).

[Effect of antianginal therapy on lipid peroxidation in patients with ischemic heart disease]. / Vliianie antianginal'noi terapii na perikisnoe okislenie lipidov u bol'nykh ishemicheskoi bolezn'iu serdtsa.

Measurement of the blood lipid peroxidation products (lipid hydroperoxides, dienic ketones, and malonic dialdehyde) was carried out in 26 patients with stable angina of effort and in 31 patient with postinfarction cardiosclerosis with due regard for the ejection fraction (intact, reduced) before treatments administration and after institution of antianginal therapy (nitrates, beta-adrenoblockers, nifedipine). The antianginal therapy has been shown to have but insignificant effect on both blood plasma contents of dienic ketones and plasma/erythrocyte content of malonic dialdehyde, which fact is regarded as an indication for use of antioxidant agents.

[The evaluation of pharmacological tests with nitroglycerin, anaprilin, korinfar and No-Shpa in patients with stable stenocardia of effort]. / Otsenka farmakologicheskikh prob s nitroglitserinom, anaprilinom, korinfarom i no-shpoi u bol'nykh so stabil'noi stenokardiei napriazheniia.

Acute pharmacological tests were done in 47 patients with stable II-III functional class angina of effort. Indices for central hemodynamics were determined with the aid of Iu. T. Puskar' modification thoracic rheovasography techniques. In the acute test in patients with exertional angina, nitroglycerin, anaprilin, corinfar, and no-shpa tend to reduce energy expenditure on displacement of one litre of cardiac output, with corinfar being also capable of lowering total peripheral vascular resistance, no-shpa tending to augment the cardiac index and reduce total peripheral vascular resistance 30 minutes after the intake of the drug (but this effect is but of short duration: it lasts for only 30 minutes).

[The function of the thyroid and thyrotropic function in patients with chronic ischemic heart disease and rhythm disorders]. / Funktsional'noe sostoianie shchitovidnoi zhelezy i tireotropnaia funktsiia u bol'nykh khronicheskoi ishemicheskoi bolezn'iu serdtsa s narusheniiami ego ritma.

Measured in 119 patients with chronic heart disease (exercise-induced angina in 62, cardiosclerosis in 57 cases) presenting with arrhythmias (extrasystolic arrhythmia, permanent form cardiac fibrillation, association of cardiac fibrillation with ventricular arrhythmia, with n = 58, 38, 23 respectively) were blood levels of thyroid-stimulating hormone (TSH), triiodothyronine (T3) and thyroxin (T4) using immunoradiometric assay. In extrasystolic arrhythmia, permanent form cardiac fibrillation, there were no deviations from the norm in the basal TSH blood levels, reduction in (T3) as well as augmentation of (T4) in cardiac fibrillation. With permanent form cardiac fibrillation associated with ventricular arrhythmia the TSH blood level got decreased, the (T3) and (T4) content undergoing no changes The posttreatment blood content of (T3) tended to augment in extrasystolic arrhythmia.

[The impact of the intravenous He-Ne laser therapy on the antioxidant system in patient with stable exertion angina and postinfarct cardiosclerosis]. / Vliianie vnutrivennoi gelii-neonovoi lazernoi terapii na antioksidantnuiu sistemu u bol'nykh stabil'noi stenokardiei napriazheniia i postinfarktnym kardiosklerozom.

The authors' study show that intravenous He-Ne laser therapy (HNLT) in patients with stable angina of effort (functional class II-III) and postinfarction cardiosclerosis irrespective of ejection fraction increased plasma katalase and red cell vitamin A concentrations. HNLT aroused vitamin E concentration in red cells in anginal patients with intact ejection fraction whereas in those with reduced ejection fraction it elevated blood peroxidase, plasma vitamin A and E concentrations. For patients with postinfarction cardiosclerosis there were, respectively, higher levels of blood peroxidase, plasmic vitamin A, red cell vitamin E, plasmic SH-groups and blood peroxidase, plasmic vitamins A and E.

[A comparative evaluation of the efficacy of magneto- and laser therapy in patients with osteoarthrosis deformans]. / Sravnitel'naia otsenka éffektivnosti magnito- i lazeroterapii bol'nykh deformiruiushchim osteoartrozom.

A comparative evaluation of efficacy of magneto- and laser therapy was carried out in 82 patients with osteoarthrosis deformans. The magnetic field and laser irradiation dispelled the pain syndrome and synovitis manifestations. It is recommendable that the multiple-modality therapy of patients with osteoarthrosis deformans should involve magneto- and laser therapy (15 to 20 procedures per one course) that improve results of the treatment being received and allow the time of hospitalization to be reduced at an average by 5 bed-days. Laser appeared to be a very effective mode of treatment. No unfavourable side effects were recordable.

[Methodological bases for the training of a therapist in cardiology in light of physician certification]. / Metodicheskie osnovy podgotovki terapevta po kardiologii v svete attestatsii vrachei.

In the course of theoretical education, one of the most important forms is that of lectures, particularly generalizing and problem-solving ones. Practical education (two thirds of the working time) will include the following: keeping patients under observation; practical studies; clinical and clinicoanatomical conferences; professor's rounds; going on duty by departments; participation in conducting and mastering the instrumental methods of investigation. The role of the audience at the lectures is an active one, that of the teacher is to direct and correct. Special attention is payed to individual work of a physician. All of the aforementioned kinds of work will, we believe, help the physician in making progress, upgrading his clinical mentality, attaining knowledge, skills, deontological principles in work. Use of test questions in cardiology approved by Ministry of Health of Ukraine as a national programme for certification of physicians together with the traditional methods of teaching will improve the quality of physician training.

[The interrelationship of hemodynamic indices with the phasic structure parameters of the left ventricle in hypertension patients]. / Vzaimosviaz' nekotorykh gemodinamicheskikh indeksov s pokazateliami fazovoi struktury levogo zheludochka serdtsa u bol'nykh gipertonicheskoi bolezn'iu.

Overall one hundred patients with stage II hypertensive disease (HD) were studied for central haemodynamics and chronocardiometric estimators of the left ventricle (LV) of the heart. Correlation coefficients were calculated between haemodynamic indexes and values for (LV) phase structure. In stage II HD, the above correlations were found to be dependent upon the type of central haemodynamics. But irrespective of the type of blood circulation, there was an inverse correlation between the index exertion-time and phase of slow filling, which fact is believed to be a compensatory mechanism in cardiac performance under stage II HD.

[The classification of myocardiodystrophies]. / O klassifikatsii miokardiodistrofii.

The importance of singling out myocardial lesions of non-coronary genesis. A classification of myocardiodystrophies is presented. The problem of etiology, pathogenesis, clinical and treatment of myocardial dystrophies is discussed.

[The interrelationship between humoral factors and the indices of left ventricular myocardial hypertrophy in hypertension]. / Vzaimosviaz' nekotorykh gumoral'nykh faktorov s pokazateliami gipertrofii miokarda levogo zheludochka serdtsa pri gipertonicheskoi bolezni.

Left ventricular myocardium hypertrophy, adrenocorticotropin, cortisol, renin and aldosterone were evaluated in 100 patients subdivided in three groups depending on the type of central hypertensive disease of stage two hemodynamics. Their correlation coefficients were assessed before and after treatment. It was found that patients with hypertensive disease (stage II) did not show any regularities in the correlation between the content of hormones in the blood and signs of left ventricular myocardium hypertrophy. Hence, aldosterone, renin, ACTH, cortisol do not essentially influence the development of left ventricular myocardium hypertrophy.

[The rate and time indices of mitral and tricuspid valve movement during the cardiac cycle in congenital heart defects]. / Skorostnye i vremennýe pokazateli dvizheniia mitral'nogo i trikuspidal'nogo klapanov vo vremia serdechnogo tsikla pri nekotorykh vrozhdennykh porokakh serdtsa.

Ultrasonic Doppler echotachocardiogram of the mitral and tricuspid valves together with polycardiogram were recorded in 44 patients with interatrial septal defect and in 18 patients with interventricular septal defect. The patients with interatrial septal defect manifested an increase of the velocity of the movement of the mitral valve during its opening, deceleration of the movement velocity in the atrial systole, a tendency towards movement deceleration during the closure, and a rise of the time of the mitral valve during its closure and opening. In interventricular septal defect, there was a tendency towards deceleration of the movement velocity of the mitral valve in the atrial systole. The velocity and time parameters of the movement of the tricuspid valve remained unchanged in patients with congenital defects under study.

[Prognostic value of cardiac rhythm in acute myocardial infarction]. / Prognosticheskoe znachenie serdechnogo ritma pri ostrom infarkte miokarda.

A computer-assisted special calculating complex to analyze a dynamic series of 128 successive R-R ECG intervals in 42 patients with acute myocardial infarction is described. It was established that statistical indices of the rhythm allow to evaluate the degree of severity of the disease, the reserve of adaptation possibilities of the body and predict the course of the disease.

[Cardiac hemodynamic variants in the development of heart failure in patients with postinfarct cardiosclerosis]. / Kardiogemodinamicheskie varianty razvitiia serdechnoi nedostatochnosti u bol'nykh postinfarktnym kardiosklerozom.

The cardiac hemodynamics and diastolic function of the left ventricle was studied by means of echocardiography in 133 patients with postinfarction cardiosclerosis allowing to distinguish hypertrophic and dilated types of myocardial lesions. It is emphasized that the character of the lesions should be considered in the choice of adequate treatment.