RESUMO
Evaluated long-term neuropsychological outcome of 20 high risk infants with intracranial hemorrhage (ICH) during the neonatal period who appeared free of significant impairment through 30 months of age. This group was compared with a matched sample of 20 high risk infants without intracranial hemorrhage and a group of 70 children with no history of perinatal or chronic health problems. A comprehensive neuropsychological evaluation at age 5 revealed that the two high risk groups tended to perform at a lower level than the control group across most measures. However, the ICH group performed at a significantly lower level than the control group on measures of perceptual-motor skills and intermodal memory abilities while the high risk group without ICH did not. The implications of differences in level and pattern of performance are discussed along with the implications of the current findings for long-term functioning of high risk infants with ICH.
Assuntos
Hemorragia Cerebral/psicologia , Cognição , Pré-Escolar , Feminino , Seguimentos , Humanos , Lactente , Recém-Nascido , Gravidez , RiscoRESUMO
The relationship between a fragile site on the X chromosome and autism has been well documented. The authors report a three-year-old child with partial duplication of the short arm of chromosome Y, who had an autistic disorder. He was microcephalic, but otherwise had a normal phenotype. There was a history of preterm birth and maternal diabetes. This is the sixth case of sex chromosome Y aneuploidy associated with autism, but the first with an isodicentric Y. In well-substantiated cases of autism, clinicians should now consider abnormalities of the Y as well as the X chromosome.
Assuntos
Transtorno Autístico/genética , Aberrações dos Cromossomos Sexuais/genética , Cromossomo Y , Transtorno Autístico/diagnóstico , Pré-Escolar , Sondas de DNA , Humanos , Cariotipagem , Masculino , Exame Neurológico , Aberrações dos Cromossomos Sexuais/diagnósticoRESUMO
The conservation abilities of middle-aged and elderly adults were compared. The design was a 3 (noninstitutionalized middle-aged, noninstitutionalized elderly, and institutionalized elderly) x 2 (male and female) x 3 (substance, weight, and volume conservation) x 2 (judgment and explanation responses) factorial design. The results of both an analysis of variance and correlational analyses indicated that age was not significantly related to conservation performance. Likewise, no significant institutionalization or sex effects were obtained. However, correlational analyses yielded a significant positive relationship between education and conservation.
