1.
Farmaco
; 58(12): 1283-8, 2003 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14630240
RESUMO
A series of N-aryl- or N-(1,2,4-triazol-yl)-phthalimides (4a-4i) have been synthesized starting from phthalic anhydride (1) and an appropriate amine (2a-2i). All compounds presented hypolipidemic activity, but compound 4d proved to be the most active and reduced plasma cholesterol and triglyceride levels in Swiss white mice significantly.