The flow behavior and sealing ability of calcium silicate root canal cement containing dimethyl sulfoxide: An in vitro study.

INTRODUCTION: To develop a calcium silicate (CaSi)-based cement containing dimethyl sulfoxide (DMSO) and cement deliver device for new root canal filling technique, and to assess the flow behavior, leakage, and root canal filling quality of CaSi containing DMSO. METHODS: CaSi containing DMSO (CSC-DMSO) and CaSi containing PEG (CSC-PEG) were prepared, and the flow characteristics of both cements were compared in gypsum and resin channels using a high-speed camera. Eight root canals were obturated by CSC-DMSO or CSC-PEG using a cement delivery device, and root canal filling quality was assessed in terms of filling length using periapical radiographs. The filling length was evaluated by 'apico-coronal extension,' measuring length in reference to apical constriction. Microleakage was measured for thirty human molars that were randomly filled with CSC-DMSO, CSC-PEG, or gutta-percha and AH plus. Preliminary obturation of CSC-DMSO with cement delivery device in human teeth was analyzed in terms of filling length and void, using periapical radiographs. Statistical analysis was performed with the Kruskal Wallis test for simulated root canal fillings and one-way ANOVA for leakage test. RESULTS: The flow speed of CSC-DMSO reduced in gypsum channels compared to resin channels, but CSC-PEG did not exhibit significant differences in the channels. The median absolute value of apico-coronal extension was significantly lower in CSC-DMSO compared to CSC-PEG (p < 0.05). Microleakage did not statistically differ between the groups (p > 0.05). In the preliminary obturation, the mean apico-coronal extension of CSC-DMSO was -0.297 ± 0.724 mm, while CSC-PEG was not feasible due to excess apical extrusions. CONCLUSIONS: CSC-DMSO could be considered as an alternative filling material for root canal obturation.

Effects of lubricant-fuel mixing on particle emissions in a single cylinder direct injection spark ignition engine.

Gasoline direct injection (GDI) engines emit less carbon dioxide (CO2) than port fuel injection (PFI) engines when fossil fuel conditions are the same. However, GDI engines emit more ultrafine particulate matter, which can have negative health effects, leading to particulate emission regulations. To satisfy these regulations, various studies have been done to reduce particulate matter, and several studies focused on lubricants. This study focuses on the influence of lubricant on the formation of particulate matter and its effect on particulate emissions in GDI engines. An instrumented, combustion and optical singe-cylinder GDI engine fueled by four different lubricant-gasoline blends was used with various injection conditions. Combustion experiments were used to determine combustion characteristics, and gaseous emissions indicated that the lubricant did not influence mixture homogeneity but had an impact on unburned fuels. Optical experiments showed that the lubricant did not influence spray but did influence wall film formation during the injection period, which is a major factor affecting particulate matter generation. Particulate emissions indicated that lubricant included in the wall film significantly affected PN emissions depending on injection conditions. Additionally, the wall film influenced by the lubricant affected the overall particle size and its distribution.

Organocatalytic enantioselective synthesis of acyclic pyrimidine nucleosides by aza-Michael reaction.

An efficient diarylprolinol triphenylsilyl ether-catalyzed enantioselective aza-Michael reaction of pyrimidines as N-centered nucleophiles to α,ß-unsaturated aldehydes, followed by reduction, provided chiral acyclic pyrimidine nucleosides in good yields (51-78% yields for two steps) and excellent enantioselectivities (91-98% ee). In addition, the chiral acyclic pyrimidine nucleoside having the tert-butyldiphenylsilyl-protected hydroxyl substituent was successfully applied to the synthesis of the corresponding chiral cyclic pyrimidine nucleoside analogue bearing the tetrahydrofuranyl ring.