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PLoS One ; 18(11): e0294132, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37956128

RESUMO

This prospective, multicenter, randomized study aimed to compare the 1-year clinical outcomes after primary stenting with self-expanding bare metal nitinol stent (SENS) and plain old balloon angioplasty (POBA) in patients with critical limb ischemia (CLI) and below-the-knee (BTK) lesions. Overall, 119 patients with CLI and BTK lesions were randomized to POBA alone (POBA group, 61 patients) or primary stenting with SENS (stenting group, 58 patients) after achieving acceptable POBA results in target BTK lesions. Clinical outcomes including amputation and revascularization rates were prospectively compared for 1 year. After 1 year, similar incidence rates of individual clinical endpoints, including cardiac death (6.5% vs. 5.1%, p > 0.999), myocardial infarction (1.6% vs. 0.0%, p > 0.999), repeat revascularization (19.6% vs. 18.9%, p = 0.922), target lesion revascularization (13.1% vs. 17.2%, p = 0.530), and amputation (4.9% vs. 0.0%, p = 0.244), were observed. POBA appeared to have acceptable treatment outcomes compared with primary stenting with SENS after 1 year in CLI patients with BTK lesions undergoing percutaneous transluminal angioplasty (PTA).


Assuntos
Angioplastia Coronária com Balão , Angioplastia com Balão , Doença Arterial Periférica , Humanos , Estudos Prospectivos , Angioplastia com Balão/efeitos adversos , Angioplastia com Balão/métodos , Stents , Resultado do Tratamento , Grau de Desobstrução Vascular , Artéria Poplítea , Doença Arterial Periférica/terapia
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