RESUMO
Behavioral issues are a frequent problem in the pediatric population. Often, these are evaluated and considered to be psychiatric in origin. We report on a pediatric patient who presented with severe behavioral disturbance and developed organic symptoms including hypoventilation and dysautonomia and who was ultimately diagnosed with ROHHADNET syndrome, a syndrome of rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation associated with a neuroendocrine tumor. Autopsy findings revealed novel findings of the syndrome, including hypothalamic encephalitis.
Assuntos
Neoplasias das Glândulas Suprarrenais/complicações , Doenças do Sistema Nervoso Autônomo/complicações , Transtornos do Comportamento Infantil/etiologia , Ganglioneuroblastoma/complicações , Doenças Hipotalâmicas/complicações , Hipoventilação/complicações , Neoplasias das Glândulas Suprarrenais/patologia , Doenças do Sistema Nervoso Autônomo/patologia , Encéfalo/patologia , Pré-Escolar , Evolução Fatal , Feminino , Ganglioneuroblastoma/patologia , Humanos , Hiperfagia/complicações , Doenças Hipotalâmicas/patologia , Obesidade , SíndromeRESUMO
Leclercia adecarboxylata, a gram-negative bacillus of the Enterobacteriaceae family, is rarely identified as a pathogen in humans. We describe a fatal case of L adecarboxylata sepsis in a child. This is the first reported pediatric death associated with infection due to L adecarboxylata.
