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J Cutan Med Surg ; 20(2): 135-8, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26318546

RESUMO

BACKGROUND AND OBJECTIVE: Activity of vitiligo has not been considered as a patient selection criteria in previous studies; we decided to compare the presence of elevated thyroid auto-antibodies in patients with progressive and stable vitiligo. METHODS: Seventy-two patients with vitiligo were examined for thyroid problems and were divided into 2 groups of stable and progressive vitiligo according to their history and physical examination. Anti-thyroid peroxidase antibodies (anti-TPO antibodies), thyroxine (T4), and thyroid stimulating hormone (TSH) levels were assessed for all patients. RESULTS: Elevated levels of anti-TPO antibodies were observed in 43.7% of the patients with stable vitiligo and in 37.5% of patients with progressive vitiligo, which was not statistically significant (P = .315). CONCLUSION: This study not only confirmed thyroid dysfunction in patients with vitiligo but also showed that there was no difference in thyroid dysfunction and anti-TPO antibody levels in the subgroups of patients with stable or progressive vitiligo.


Assuntos
Autoanticorpos/imunologia , Autoantígenos/imunologia , Iodeto Peroxidase/imunologia , Proteínas de Ligação ao Ferro/imunologia , Tireoidite Autoimune/complicações , Vitiligo/complicações , Adulto , Estudos de Casos e Controles , Progressão da Doença , Feminino , Humanos , Masculino , Estudos Prospectivos , Tireoidite Autoimune/diagnóstico , Tireoidite Autoimune/imunologia , Tireotropina/imunologia , Vitiligo/diagnóstico , Vitiligo/imunologia
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