RESUMO
Sinus histiocytosis with massive lymphadenopathy, Rosai-Dorfman disease (RDD) rarely involves the central nervous system. Previously reported lesions in the spine were primary occurrences. We report a patient who developed presumed secondary symptomatic involvement of the spine five years following therapy for a primary intracranial RDD.
Assuntos
Vértebras Cervicais/patologia , Fossa Craniana Posterior/patologia , Histiocitose Sinusal/patologia , Neoplasias da Medula Espinal/patologia , Doenças da Coluna Vertebral/patologia , Adolescente , Adulto , Vértebras Cervicais/fisiopatologia , Feminino , Histiocitose Sinusal/complicações , Humanos , Imunossupressores/uso terapêutico , Imageamento por Ressonância Magnética , Masculino , Prednisolona/uso terapêutico , Radioterapia , Neoplasias da Medula Espinal/fisiopatologia , Doenças da Coluna Vertebral/etiologia , Doenças da Coluna Vertebral/fisiopatologia , Espaço Subaracnóideo/patologia , Espaço Subaracnóideo/fisiopatologia , Espaço Subdural/patologia , Espaço Subdural/fisiopatologia , Resultado do TratamentoRESUMO
Malignant fibrous histiocytoma (MFH) is a morphologically ill-defined tumour of the soft tissues and may involve nearly every organ of the body. MFH of the spermatic cord represents an extremely rare entity and reports of it in the literature are limited. We report a 69-year-old man found to have a left spermatic cord MFH and retroperitoneal and mediastinal lymphadenopathy, who was treated with radical orchiectomy and adjuvant chemotherapy. The morphological findings of the spermatic tumour are presented and the literature is reviewed to clarify the potential diagnostic/therapeutic approaches and the prognosis related to spermatic cord MFH.
