[Clinico-morphological characteristics of esthesioneuroblastoma with extensive dissemination of the neoplastic process]. / Kliniko-morfologicheskie osobennosti éstezioblastomy s obshirnym rasprostraneniem opukholevogo protsessa.

Eight disseminated esthesioblastomas were investigated. The specific features of these cases were: prolonged development of the disease prior to correct diagnosis (up to 2 years), tumor dissemination outside the nose and paranasal sinuses, and mixed morphological changes indicating various tumor types.

[The generalized form of Rendu-Osler-Weber disease (a practical case)]. / Generalizovannaia forma bolezni Randiu-Oslera-Vebera (sluchai iz praktiki).

The article presents clinical and pathomorphological findings related to a case of the Rendu-Osler-Weber disease and demonstrates the difficulties of its differential diagnosis.

[Hormonal induction of liver tyrosine aminotransferase in animals with chronic poisoning by hepatotropic poisons]. / Gormonal'naia induktsiia tirozinaminotransferazy pecheni zhivotnykh v usloviiakh khronicheskoi intoksikatsii nekotorymi gepatotropnymi iadami.

A study has been made of the effect of ethanol and CCl4 on hormonal induction of tyrosine aminotransferase in mouse liver. Both the hepatotropic poisons administered for a long time lose the induction effect and considerably reduce the same effect exerted by hydrocortisone. Microscopic study has revealed fatty dystrophy of the liver cells and even the formation of the areas of necrosis as a result of administering CCl4. The liver tissue stroma has been shown to develop reactive inflammation.

The microspectrophotometric research of the content of ascorbic acid in carcinomas of the uterine cervix.

Taking into consideration the fact that the ascorbic acid takes an active part in the process of growth and reproduction of the cells, the authors have undertook the microspectrophotometric research of its content in 27 different structure cancerous tumours of the uterous cervix. The result of the research showed the decrease of the quantity of ascorbic acid in cancerous tumours of the uterous cervix in compare with norm. The content of ascorbic acid in carcinomas cancerous tumours of the uterine cervix depends on the degree of differentiation and histogenesis of the neoplasm. In less differential squamous cell cancers the quantity of ascorbic acid is more than in the mature ones. The least quantity of ascorbic acid is in adenogenic carcinomas of the uterine cervix. The micro-spectro-photometric research of the content of ascorbic acid in cancerous tumours of the uterine cervix may be used as test in practical activity of the pathologoanatomist for the differential diagnostic and prognosis.

[Microspectrophotometric study of the content of various metabolites in cervical cancer]. / Mikrospektrofotometricheskoe issledovanie soderzhaniia nekotorykh metabolitov v rakovykh opukholiakh sheiki matki.

The composite microspectrophotometric study of the content of DNA, PAS-positive, alcian-positive substances, lipids, and the activity of succinate dehydrogenase and ascorbic acid in the cervical epithelium normally and in cancer tumors showed preinvasive forms of cancer to be characterized by increased polyploidy, content of DNA and lipids, and increased activity of succinate dehydrogenase, and decreased content of glycogen, acid mucopolysaccharides and ascorbic acid. Invasive forms of cancer are characterized by more marked changes in these values.