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1.
Med J Malaysia ; 74(3): 205-208, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31256174

RESUMO

OBJECTIVE: Chronic suppurative otitis media (CSOM) usually begins as a spontaneous perforation of tympanic membrane due to an acute infection of the middle ear. This study was aimed to evaluate the association between allergy and CSOM. METHODS: A case-control study was carried out among patients with CSOM (cases) and controls were those with no ear pathology. The presence of CSOM was made through a medical history and otoscopic examination. Allergen testing was done by the skin prick test. RESULTS: In all 124 subjects were recruited in this study with equal number of the cases and controls. The commonest positive reaction in the skin prick test in both groups was to house dust mites. Among CSOM cases, half (50%) of them had an allergy to Blomia tropicalis and 48.4% to Dermatophagoides while in the control group, 27.4% to Dermatophagoides and 25.8% to B. tropicalis. There were significant associations between CSOM and allergy to B. tropicalis (p=0.005), Dermatophagoides (p=0.016) and Felis domesticus (p=0.040). The prevalence of allergy at 95% confidence interval (95%CI) in CSOM and control groups were demonstrated as 59.7% (95%CI: 47.5, 71.9) and 30.6 % (95%CI: 19.1, 42.1) respectively. There was a significant association between allergy and CSOM (p=0.001). CONCLUSION: Indoor allergens are the most prevalent in our environment and therefore good control may difficult to achieve. The hypersensitivity states of the subject are likely to have a role in the pathogenesis of CSOM especially in the tropical countries where allergy occurs perennially.


Assuntos
Hipersensibilidade/epidemiologia , Otite Média Supurativa/complicações , Adolescente , Adulto , Estudos de Casos e Controles , Doença Crônica , Feminino , Humanos , Malásia , Masculino , Pessoa de Meia-Idade , Prevalência , Adulto Jovem
2.
Med J Malaysia ; 68(2): 181-2, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23629574

RESUMO

Sensorineural hearing loss following trauma is a common finding in daily clinical practice and usually associated with a poor prognosis. Our case illustrates a patient who was involved in motor vehicle accident sustaining bilateral severe to profound sensorineural hearing loss but subsequently recovered fully after two years. Unless there is clear trauma to the cochlea or auditory nerve, a substantial duration of follow up is needed in the treatment of such cases.


Assuntos
Perda Auditiva Bilateral , Perda Auditiva Neurossensorial , Acidentes , Cóclea , Humanos , Veículos Automotores
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