RESUMO
The paper shows the high therapeutical efficiency of combined He-Ne laser therapy in patients with coronary heart disease. Its effect on the thromboxane-prostacyclin system is one of the mechanisms of laser impact. The combined He-Ne laser therapy promotes normalization of the level of thromboxane B2 and its ratio to the metabolite prostacyclin.
Assuntos
Angina Pectoris/sangue , Terapia a Laser , Prostaglandinas/metabolismo , Prostaglandinas/efeitos da radiação , Adulto , Idoso , Angina Pectoris/metabolismo , Epoprostenol/sangue , Epoprostenol/metabolismo , Epoprostenol/efeitos da radiação , Humanos , Pessoa de Meia-Idade , Prostaglandinas/sangue , Tromboxano B2/sangue , Tromboxano B2/metabolismo , Tromboxano B2/efeitos da radiação , Tromboxanos/sangue , Tromboxanos/metabolismo , Tromboxanos/efeitos da radiação , Fatores de TempoRESUMO
There was a relationship of the degree of imbalance between thromboxane and prostacyclin, prostaglandins (PG) F2 alpha and E1 in patients with coronary heart disease concurrent with stable angina pectoris. A significant increase in the levels of thromboxane and PGF2 alpha was found with relative prostacyclin and PGE1 deficiency during graded exercise at the moment of transient myocardial ischemia; the imbalance significantly increased as exercise tolerance decreased. Transient myocardial ischemia induced by transesophageal left atrial pacing revealed unidirectional changes in plasma PG, as did exercise.