[Superoxide dismutase activity in microsomes of functionally different rat tissues in vitamin E deficiency]. / Aktivnost' superoksiddismutazy v mikrosomakh funktsional'no razlichnykh tkanei krys pri nedostatochnosti vitamina E.

Comparative investigation of microsome superoxide dismutase activity in functionally different rat tissues such as lung and liver has been carried out. Modification of superoxide dismutase fraction isolated from lung and liver microsomes and SOD-activity evaluation by means of superoxide radical-dependent pyrogallol autooxidation method have been described in detail. SOD-activity has been shown to be connected with the degree of lipid peroxidative oxidation (LPO) and total condition of tissue antioxidative system in case of different E-vitamin security in various functional types of cells (alveolocytes and hepatocytes).

[Antioxidant effect of a phospholipid complex isolated from marine organisms]. / Antioksidantnoe deistvie fosfolipidnogo kompleksa, vydelennogo iz morskikh organizmov.

Antioxidative effect of phospholipid complex from the sea organisms (preparation "Kalmofil") is observed comparatively with other phospholipid fractions of animal and plant origin. Most antioxidative action of the phospholipid complex from Mollusca (preparation "Kalmofil") on the nonenzymatic LPO reactions in vitro is established. Analogous fractions from different functional animal tissues have not such influence. Application of "Kalmofil" in vivo under experimental rat hepatitis provoked by CCl4 has a corrective effect on both nonenzymatic and Fe(2+)- and NADP.H-depending LPO reactions. This preparation decreases toxic influence of CCl4 and improves antioxidative system of rat hepatocytes.