[The clinico-laboratory criteria of brain death in neurosurgical patients]. / Kliniko-laboratornye kriterii smerti mozga u neirokhirurgicheskikh bol'nykh.

With the purpose of developing scientifically substantiated criteria for brain death complex of clinical and physiological, biochemical, physicochemical, and morphological studies was initiated in 55 patients in a critical state because of a dangerous craniocerebral injury, tumours, and vascular affections of the brain. Generalized in the paper are well-known parameters characterizing irreversibility of changes. The following items are to be regarded as the principal criteria for brain death at the present stage of development of medicine: death of truncus cerebri and irreversibility of metabolic disturbances in brain activity.

[Microsurgical anatomy of a large size tumor of vestibulo-cochlear nerve]. / Mikrokhirurgicheskaia anatomiia opukholi preddverno-ulitkovogo nerva bol'shogo razmera.

The microsurgical anatomy peculiarities of a large size tumor of n. vestibulocochlearis (NVC) were studied, basing on intraoperative (in 380 patients) and sectional (30) observations data. The distinguishing of three main anatomic-topographical variants of a large size NVC tumor growth has great significance for elaboration of the microsurgical tumoral excision method.

[Microsurgical anatomy of cholesteatoma of posterior cranial fossa]. / Mikrokhirurgicheskaia anatomiia kholesteatomy zadnei cherepnoi iamki.

Microtopographical interrelations of the posterior cranial fossa structures in the presence of cholesteatoma were studied up intraoperatively in 36 cases and while the pathomorphological investigation conduction in 6 sectional observations. Cholesteatoma mostly localizes in cerebellopontile angle and more rarely--in the IV ventricle with craniospinal spreading. It is the tumor's capsule texture what causes dense adherence of cholesteatoma with surrounding cranial nerves, vessels, incorporated frequently in her structure together with underlying cerebral substance.

[Causes of disorders of vitally significant functions in surgical treatment of extracerebral parastem tumors of the posterior cranial fossa]. / Prichiny narusheniia zhiznenno vazhnykh funktsii pri khirurgicheskom lechenii vnemozgovoi parastvolovoi opukholi zadnei cherepnoi iamki.

The postoperative period course and an autopsy data of 68 patients operated on for n. vestibulocochlearis neurinoma, parasternal meningioma, cholesteatoma. Principal damaging factors and cerebral stem functional disorders are assigned.

[The effect of low doses of long-term internal irradiation on the ultrastructure and intensity of lipid peroxidation in rat brain and blood]. / Vliianie malykh doz dlitel'nogo vnutrennego radiatsionnogo vozdeistviia na ul'trastrukturu i intensivnost' perekisnogo okisleniia lipidov v golovnom mozge i krovi krys.

Rats were administered with the mixture of 137Cs and 85Sr for 30, 56 and 90 days. Dynamic of ultrastructural changes of lipid peroxidation has been studied in cerebrum and blood. Maximum biochemical changes have been detected after radionuclide administration for 30 days (increase in spontaneous chemiluminescence intensity and quantity of TBA-active products). Under further administration lipid peroxidation parameters as well as radionuclide content in blood and organs were sufficiently stable, while ultrastructural changes were in progress during the influence.

[Microsurgical anatomy of meningioma of the posterior cranial fossa]. / Mikrokhirurgicheskaia anatomiia meningiomy zadnei cherepnoi iamki.

On the material of 107 intraoperative and 19 section specimens, a topographic anatomy of meningiomas of the posterior cranial fossa was studied. The groups of tumours were distinguished, depending on location of primary meningioma and direction of its growth. Tumour interrelations with the caudal cranial nerves and surrounding vessels were studied.

[Topographoanatomic prerequisites for radical surgery of craniopharyngiomas]. / Topografoanatomicheskie predposylki radikal'nykh operatsii pri kraniofaringiomakh.

Sixty-seven patients with craniopharyngioma were tested by total (41) or subtotal (26) resection of the tumor. The possibility for radical removal of a craniopharyngioma depends on the size of the tumor and the character of its growth and on the peculiarities of its relation with the abjoining structures, i.e. the sella turcica, third ventricle, optic chiasm, and the vessels of the cerebral base. The tendency to perform radical operations for endosuprasellar craniopharyngiomas may be undertaken if it is possible to achieve atraumatic separation of the capsule of the tumor from the structures forming its seat under the floor of the third ventricle. The results of radical interventions for suprasellar intraventricular craniopharyngiomas are less favourable due to the marked macro- and microstructural changes in the hypothalamic and thalamic parts of the brain.