New triterpenoids from the fruiting bodies of Ganoderma lucidum and their bioactivities.

Phytochemical investigation of the AcOEt extract of G. Lucidum has led to the isolation of two new triterpenoids, 1 and 2, together with five known ones, 3-7. The structures of the new compounds were identified as 12ß-acetoxy-3ß,7ß-dihydroxy-11,15,23-trioxolanost-8-en-26-oic acid butyl ester (1) and 12ß-acetoxy-3,7,11,15,23-pentaoxolanost-8-en-26-oic acid butyl ester (2) on the basis of detailed spectroscopic analysis (mass spectrometry, and 1D- and 2D-NMR experiments). The antimicrobial activities of 1 and 2 were also evaluated.