[The characteristics of the development of cataleptic phenomena during the action of a new Ukrainian neuroleptic--a butyrophenone derivative--in experiments on mice]. / Osoblyvosti rozvytku kataleptychnykh iavyshch pry diï novoho vitchyznianoho neiroleptyka--pokhidnoho butyrofenonu v eksperymenti na myshakh.

There are studying the symptoms of development catalepsy at new home preparation, which is having the butirophenone's derivative. There are shown that the time development and manifestation of catalepsy are depending from preparation's dose: 0.1 mg/kg-1.3 mg/kg (maximum) -10 mg/kg in intravenous introduction and 1.2 mg/kg-3.5 mg/kg (maximum)-40 mg/kg in intraperitoneal introduction.

[Spasmophilia in children and the anticonvulsant properties of a new Ukrainian preparation containing a pyrimidine derivative]. / Spazmofiliia u ditei ta protysudomni vlastyvosti novoho vitchyznianoho preparatu, shcho vmishchuie pokhidnyi pirymidynu.

Tablets valcophen, which are containing the pyrimidine's derivative, have an acute anticonvulsive activity. Tablets valcophen and granules phenobarbital for children are having the same activity, which have been marked about lower intensity convulsions, quantity of a lived animals and also lengthening a time of deathing mice. These investigations are showing that tablets valcophen may be used for treatment convulsive state in children.

[The physiological properties of the action of a new analgesic and antipyretic preparation]. / Fiziolohichni vlastyvosti diï novoho anal'getychnoho i zharoznyzhuval'noho preparatu.

Children's morbidity from Chernobyl accident aftereffects was studied. New preparation "Paravit" was created. This preparation is for treatment illnesses, which are accompanied by pain and slight temperature. Tablets "Paravit" have mark, which allows exact dosing for children of different age. The specific pharmacological investigation of "Paravit" were taken. They showed that new preparation possesses active antipyretic and analgetic properties.

[The effect of Val'kofen tablets for children on the function of the gastrointestinal tract and liver in an experiment]. / Vplyv tabletok dlia ditei "Val'kofen" na funktsional'nyi stan shlunkovo-kyshkovoho traktu ta pechinku v eksperymenti.

It was prepared new child's medicinal form, the tablets "Valcophene" for making a wider variety of pediatric preparation's. It is studied the influence of "Valcophene" on the functional state of alimentary canal in experiment on rat's. Results investigation's are testified to absence of ulcerative action in new child's preparations. Studying influence in liver functional state is provided for new children's preparation "Valcophene" too. The chronic experiment is showed that "Valcophene" didn't influence on liver in experimental animals.

[Paracetamol pharmacokinetics in the blood plasma of sexually immature rabbits with the use of the new Paravit preparation]. / Farmakokinetyka paratsetamolu pry zastosuvanni novoho preparatu "Paravit" u plazmi krovi statevonezrilykh kroliv.

"Paravit" tablets have been investigated. The pharmacokinetics of "Paravit" was studied on preadolescent rabbit. "Paracetamol" tablets were used for comparison. The amount of paracetamol was measured in the rabbits plasma using spectrophotometry. It is shown that the relative bioequivalence of "Paravit" was 136.7%.