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Curr Mol Med ; 19(7): 461-472, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31131752

RESUMO

The demands for genotyping techniques with acceptable precision, accuracy, cost-effectiveness in high throughput formats made driving forces for continuous development of novel technologies. A wide range of mutation detection techniques based on polymerase chain reaction (PCR) have been introduced. The best alternatives were the isothermal amplification technologies that those did not require a thermal cycler. In this review, we aimed to describe the most known isothermal amplification techniques for SNP genotyping.


Assuntos
Técnicas de Genotipagem , Reação em Cadeia da Polimerase , Polimorfismo de Nucleotídeo Único/genética , Genótipo , Humanos
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