[Dynamics of free-radical oxidation processes in transplantable sarcoma-45 as indicator of tumor and body interaction].

Induced chemoluminescence was used for 30 days to measure lipids peroxidation in transplantable sarcoma-45 homogenates in 83 noninbred male rats. It was found that tumor/body interaction can be interpreted in terms of free-radical oxidation processes taking place in tumor tissue. In the middle of the experiment, the kinetics of chemoluminescence soared up which was accompanied by slight increase in tumor mass. Later on, tumor growth involved a rise in antioxidant enzyme levels which is supposedly accounted for by the expression of the genes responsible for the rate of antioxidant reactions in general. That increase resulted in uncontrollable growth of tumor.

[Lipid peroxidation and tumor dimensions in stomach cancer]. / Zavisimost' perekisnogo okisleniia lipidov pri reake zheludka ot razmerov opukholi.

The parameters of lipid peroxidation were examined in blood serum of 40 patients with stomach cancer by induced chemiluminescence (CL)--Republican Research Center of Oncology, Healthcare Ministry of Uzbekistan. The CL parameters were demonstrated to increase alongside with the growing tumor mass. The induced CL of blood serum characterizes the status of lipid peroxidation and is a direct reflection of the body's reaction to tumor growth. The method of induced CL can be used on in clinical practice as an additional diagnostic test describing the tumor growth course in stomach cancer.

[Kinetics of free-radical oxidation of blood serum as an indicator of tumor effect on organism]. / Kinetika svobodno-radikal'nogo okisleniia syvorotki krovi kak pokazatel' vliianiia opukholi na organizm.

The experiments were made with 83 outbred male rats with transplanted sarcoma-45. The method of initiated chemiluminescence (CL) was used to measure the parameters of blood-serum lipid peroxidation in the animals. The index of free-radical blood-serum lipid peroxidation was shown to reflect in rats the tumor-body ratio. Initially, the kinetic parameters of induced CL were significantly increasing, which was accompanied by a minor remission of the tumor volume. The subsequent stages of tumor growth were associated with increasing, parameters in the studied enzymes' activity, which is apparently related with the expression of genes crucial for the body's antioxidant properties. This enables the tumor cells to escape the monitoring of non-specific cellular immunity with the result being an uncontrollable tumor-volume growth.

[Peroxidation of serum lipids in patients with breast cancer]. / Perekisnoe okislenie lipidov syvorotki krovi bol'nykh rakom molochnoi zhelezy.

Parameters of chemiluminescence of lipid peroxidation (LP), induced by hydrogen peroxide in the blood serum of oncology patients (n = 60), were examined in the process of their combined therapy. During the dynamic observations, complete correlations were found between the peculiarities of manifestations and of the clinical course of the tumor process, the level of free-radical LP and the antioxidants of blood serum. A comprehensive assessment of all mentioned indices can be used to monitor the efficiency of a conducted therapy.

Free molecular sound propagation.

The sound propagation through a gas in the free-molecular regime is studied on the basis of the linearized collisionless Boltzmann equation. The two principal quantities that characterize the sound propagation, namely the phase and amplitude of the perturbation, are determined by taking into account the influence of the receptor. It is shown that at a small distance between the source and the receptor the presence of the last changes qualitatively the sound characteristics. Two phase velocities are introduced: a differential and an integral, which are different in the free molecular regime.

Onsager-Casimir reciprocity relation for the gyrothermal effect with polyatomic gases.

On the basis of the linearized Boltzmann equation and the boundary condition for the distribution function, the Onsager-Casimir reciprocity relation is derived for polyatomic gases confined between two cylinders in the presence of a magnetic field. The cross effect, namely, the heat flux caused by the rotation of the inner cylinder is predicted. Because of the heat flux the cylinder can be heated or cooled depending on the direction of the magnetic field. This effect is coupled with the gyrothermal effect by the reciprocity relation.

[Effect of adaptation to high-altitude conditions on the circadian rhythm of the epithelial mitotic activity in the convoluted kidney tubules in white rats]. / Vliianie adaptatsii k usloviiam vysokogor'ia na sutochnyi ritm mitoticheskoi aktivnosti épiteliia izvitykh kanal'tsev pochki belykh krys.

It has been established in experiments on 280 white randombred male rats weighing 100-120 g that the lifting of the animals from the valley (820 m above the sea level) to the mountains (3379 m above the sea level) brings about within the first day marked suppression of the mitotic activity of the epithelium of involuted renal tubules. This activity increases beginning from the end of the first week, approaches the control value by the 30th day of adaptation and almost completely returns to normal by the 60th day of the animals' stay in the mountains. The circadian rhythms of the mitotic activity appeared undisturbed and was monophasic in nature.