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Biomater Sci ; 12(11): 2841-2864, 2024 May 28.
Artigo em Inglês | MEDLINE | ID: mdl-38683585

RESUMO

Polymer-based biomaterials have received a lot of attention due to their biomedical, agricultural, and industrial potential. Soluble protein-polymer bioconjugates, immobilized proteins, and encapsulated proteins have been shown to tune enzymatic activity, improved pharmacokinetic ability, increased chemical and thermal stability, stimuli responsiveness, and introduced protein recovery. Controlled polymerization techniques, increased protein-polymer attachment techniques, improved polymer surface grafting techniques, controlled polymersome self-assembly, and sophisticated characterization methods have been utilized for the development of well-defined polymer-based biomaterials. In this review we aim to provide a brief account of the field, compare these methods for engineering biomaterials, provide future directions for the field, and highlight impacts of these forms of bioconjugation.


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Polímeros , Polímeros/química , Materiais Biocompatíveis/química , Proteínas Imobilizadas/química , Proteínas/química , Humanos , Estabilidade Proteica , Animais
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