Effect of Laser Therapy on Postoperative Pain and Endodontic Retreatment: A Systematic Review and Meta-Analysis.

BACKGROUND: Root canal re-treatment (RCR) cases are considered some of the most challenging cases in the field of endodontics, as they are mostly associated with various iatrogenic errors such as ledge formation, incomplete biomechanical preparation, file separation, and incomplete obturation. These iatrogenic errors lead to defective niches within root canals that may act as reservoirs for various viable microorganisms. Such residual microbial niches may cause postoperative pain even after thorough debridement and reshaping the canals, ultimately leading to a poor prognosis for the tooth. Nowadays, prevention of postoperative pain in re-treatment cases and prognosis are effectively managed by photobiomodulation therapy (PBMT). METHOD: Relevant studies in the English language published before November 2022 were identified using electronic databases like PubMed, SCOPUS, and EBSCO to conduct bibliographic research. This systematic review is based on 3 studies that were found eligible as per the inclusion and exclusion criteria. This systematic review is in accordance with PRISMA guidelines. RESULTS: The systematic review indicated a positive impact by significantly decreasing postoperative pain in RCR cases when treated with PBMT. The variation was statistically significant at 24 hours (P = .0002), 48 hours (P = .03), and 72 hours (P = .02). The mean difference at 24 hours was 0.65 (95% CI, 0.32-0.99), at 48 hours was 0.46 (95% CI, 0.05-0.87), and at 72 hours was 0.40 (95% CI, 0.07-0.74). There was no statistical heterogenicity at 24 hours (P > .05), but a medium heterogenicity was observed at 48 hours and 72 hours. PRACTICAL IMPLICATION: PBMT or low-level laser therapy has shown superior results as compared to the conventional pharmacologic approach in postoperative pain management in RCR cases.

Concomitant Ipsilateral Intracapsular and Extracapsular Femoral Neck Fractures in Young Individuals: A Report of 3 Cases.

CASES: Concomitant ipsilateral intracapsular and extracapsular fractures of the femoral neck, also termed "segmental fracture neck femur," are rare injuries, especially in physiologically young patients. We present 3 such cases that successfully underwent operative fixation with an extramedullary implant. CONCLUSION: Good clinical outcomes may be obtained after osteosynthesis with extramedullary fixation devices in concomitant ipsilateral intracapsular and extracapsular fractures of the femoral neck in young patients (<60 years). They should be followed for a long duration to look for avascular necrosis.

Wedgeless V-Shaped Osteotomy of the Distal Medial Femur with Locking Plate Fixation for Correction of Genu Valgum in Adolescents and Young Adults.

Background: Genu valgum is a common disorder affecting adolescents and young adults. Treatment of this disorder requires restoration of normal mechanical axis alignment and joint orientation, for which it is important to assess whether the deformity arises from the distal femur, knee joint, or proximal tibia. Most commonly, the deformity originates from the distal femur, and various osteotomies of the distal femur have been described1-6. The presently described wedgeless V-shaped osteotomy7,8 is a good option among the various alternative procedures listed below. Description: The anesthetized patient is placed in the supine position on a radiolucent operating table. A bolster is placed beneath the knee to relax the posterior structures. A medial longitudinal skin incision is made that extends from the level of the medial joint line to 5 cm proximal to the adductor tubercle. The vastus medialis is identified and elevated anteriorly by detaching it from its distal and posterior aspects. The leash of vessels underneath the vastus medialis is identified, and the apex of the V-shaped osteotomy is kept just proximal to it. The anterior arm of the V is kept longer than the posterior one, both of them are kept perpendicular to each other, and the apex of the V is made to point distally. The osteotomy is performed on the medial cortex with use of an oscillating saw or multiple drill holes that are then connected using a thin osteotome. Care is taken not to utilize a saw or drill on the lateral cortex. A gentle valgus thrust is applied to break the lateral cortex without periosteal disruption. The apex of the V osteotomy on the proximal fragment is trimmed, and the deformity is corrected with varus force. The osteotomy site is stabilized with use of an anatomically contoured distal medial femoral locking plate or a medial proximal tibial L-shaped buttress plate (of the contralateral side). The implant position is verified under a C-arm image intensifier. The wound is closed in layers over a suction drain in a standard manner. Alternatives: Various types of corrective osteotomies of the distal femur have been described in the literature, including the lateral opening wedge, medial closing wedge, dome, and spike osteotomies1-6. All of these procedures have certain limitations and shortcomings. Rationale: The wedgeless V-shaped osteotomy is another described procedure that is inherently stable7,8. It is a safe procedure and yields good clinical outcomes8,9. The posterior arm of the V-shaped osteotomy is kept smaller than the anterior arm. The proximal cortical bone is allowed to dig into the cancellous bone of the wider distal metaphysis during deformity correction. Trimming the apex of proximal bone end after making the osteotomy facilitates the process. Expected Outcomes: In a study of 46 patients with a mean age of 16.9 years (range, 15 years to 23 years), Gupta et al.8 reported that the mean radiographic tibiofemoral angle improved from 22.2° (range, 16° to 29°) preoperatively to 5.1° (range, 0° to 10°) postoperatively (p < 0.001). Similarly, the mean lateral distal femoral angle improved from 79.2° preoperatively to 89.1° postoperatively (p < 0.001) and the mean mechanical axis deviation improved from 19.6 mm preoperatively to 3.7 mm postoperatively (p < 0.001). A total of 44 of 46 cases had an excellent functional outcome, with the other 2 having good outcomes. None of the patients in the study had an unsatisfactory outcome. Important Tips: It is important to keep the whole lower limb accessible to the image intensifier intraoperatively.Identification of the leash of vessels underneath the vastus medialis is important to decide the level of the osteotomy.It is important to preserve the periosteal sleeve on the lateral aspect of the femur. Acronyms and Abbreviations: CORA = center of rotation of angulationECG = electrocardiogramLDFA = lateral distal femoral angleMAD = mechanical axis deviationMPTA = medial proximal tibial angle.

Immunocytochemistry on scrape cellblock: An aid in the diagnosis of metastatic neoplasm with unknown primary: A series of four cases.

Scrape cellblock (SCB) is a novel technique to suggest possible primary site in fine-needle aspiration cytology (FNAC) smears from the liver, lung, and lymph nodes which are the common sites of metastasis of many primary tumors. Immunocytochemistry (ICC) on SCB averts the need of more invasive diagnostic procedures and gives a conclusive diagnosis. We present a series of four cases with unknown primary site, in which ICC was done on SCB to suggest possible primary site. Three of them were liver space-occupying lesions (SOL) and one from the periportal lymph node. In all four cases, wet-fixed smear for hematoxylin and eosin stain was prepared as routine procedure. FNAC was reported as metastatic adenocarcinoma in two and metastatic spindle cell neoplasm in one liver SOL. Periportal node was reported metastatic adenocarcinoma. Two hematoxylin and eosin-stained slides from each case with higher cellularity were used to scrape off the material to prepare SCB. ICC was put which gave conclusive diagnosis in all the cases. On ICC, two cases of metastatic carcinoma in the liver were diagnosed as metastatic neuroendocrine neoplasm from Gastrointestinal Tract and metastatic adenocarcinoma from the stomach. Spindle cell neoplasm of the liver was diagnosed as gastrointestinal stromal tumor from the stomach. Pancreatic head mass in metastatic periportal node was confirmed later by radiologic examination. SCB is a useful technique to make the best use of available material where reaspiration is difficult. ICC on SCB is of maximum utility to suggest possible primary sites in metastatic cases with unknown primary or where biopsy of the lesion is not possible.

Chemical, biological, radiological and nuclear training issues in India: A fresh perspective.

Appropriate training is the key to the right level of preparedness against any disaster, and Chemical, Biological, Radiological and Nuclear (CBRN) disasters are no different. The presence of contamination precludes rescue operations to commence soon after the event and it takes a systematic approach to detect and decontaminate the CBRN hazard. Achieving such interventions poses a critical challenge because humans do not possess any inborn, natural sensors with which to recognize these dangers early enough. This requires special training besides the right tools to achieve the objective. CBRN training in India has evolved over the years as a pure military-related concept to a disaster-level response training involving the first responders. The complex nature of CBRN agents requires a methodical and systematic approach to counter the response successfully, and the training for this necessitates adoption of proven modern principles of education management, like training needs analysis, operational research, etc. Simulation as a training and planning offers repeatability, controllability and the possibility for evaluation and is being successfully used in some advanced countries for training responders in the relatively unknown and mysterious domain of CBRN disaster management training. There is also a perceived need to integrate and standardize the curricula to suit the respective first responder. It is strongly felt that with the able support of apex agencies like National Disaster Management Authority and guidance of the Defence Research and Development Organisation, the training effort in CBRN disaster management will get the right impetus to achieve a stature of a modern, progressive and mature endeavour. This will enable India to develop a strong CBRN defence posture very much in line with the country's emerging status globally as a technological power.