RESUMO
The immediate and end results of combined radiotherapy for cervical carcinoma stages I-III conducted at the N.N. Blokhin Center's Clinic (1982-1996) were compared. Intracavitary irradiation was carried out using the following radiation sources: 60Co-AGAT-V (208); 137Cs-Selectron (96) and 252Cf-ANET-V and ANET-VA (115). Remote-control irradiation procedure was identical in all groups. Five-year survival for stage I was 85.1% +/- 6.2; 85.7% +/- 13.1 and 87.8% +/- 1.2; stage II--67.5% +/- 4.0; 61% +/- 8.5 and 76.6 +/- 3.2; stage III--43.6% +/- 6.8; 57.7% +/- 9.6 and 70.9% +/- 5.4, respectively. Ten-year survival for stage I was 56.9% +/- 15.1; 85.4% +/- 13.1 and 80.1% +/- 1.5; stage II--65% +/- 5.2; 46.5% +/- 8.7 and 70.7% +/- 3.5; stage III--42% +/- 8.8; 51.3 +/- 9.9 and 64.6% +/- 6.2, respectively.
Assuntos
Braquiterapia/instrumentação , Neoplasias do Colo do Útero/radioterapia , Adulto , Idoso , Califórnio/uso terapêutico , Radioisótopos de Césio/uso terapêutico , Radioisótopos de Cobalto/uso terapêutico , Feminino , Seguimentos , Humanos , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Análise de Sobrevida , Resultado do Tratamento , Neoplasias do Colo do Útero/patologiaRESUMO
The results of complex radiation therapy in 130 patients with cervical cancer were compared. Colpometrostats (components of AraT-B apparatus) with automatically-fed sources of 60Co high-level radiation were used for intracavitary treatment in 65 patients (group I). Gynecologic gamma-ray applicators with manually afterloaded 60Co low-level radiation sources were employed in group 2. No recurrence or metastasis were identified in stage I-II cases of both groups within the first 3 years of follow-up. Metastases into regional lymph nodes were detected in 3 patients (stage III) in group I and recurrences with advancing metastatic spread in 4 patients of group 2. Radiation-induced complications were relatively frequent in group 2.
