RESUMO
A total of 249 client-owned dogs with osteoarthritis were treated with firocoxib (5 mg/kg/day) or a positive control, etodolac (10-15 mg/kg/day), for 30 days. Veterinary examinations were performed on approximately days 0 (visit 1), 14 (visit 2), and 29 (visit 3). Based on defined noninferiority criteria, firocoxib and etodolac were comparable. Based on the magnitude of the change from baseline, improvement with firocoxib was significantly greater than with etodolac for lameness at a trot (visits 2 and 3) and for lameness at a walk, pain on manipulation, and range of motion (visit 3) (P < .05). In weekly owner evaluations, firocoxib provided significantly greater improvement than etodolac (P < .05) at each scoring.
Assuntos
4-Butirolactona/análogos & derivados , Anti-Inflamatórios não Esteroides/uso terapêutico , Doenças do Cão/tratamento farmacológico , Osteoartrite/veterinária , Sulfonas/uso terapêutico , 4-Butirolactona/efeitos adversos , 4-Butirolactona/uso terapêutico , Animais , Anti-Inflamatórios não Esteroides/efeitos adversos , Doenças do Cão/patologia , Cães , Etodolac/efeitos adversos , Etodolac/uso terapêutico , Feminino , Coxeadura Animal/tratamento farmacológico , Masculino , Osteoartrite/tratamento farmacológico , Osteoartrite/patologia , Amplitude de Movimento Articular/efeitos dos fármacos , Amplitude de Movimento Articular/fisiologia , Segurança , Sulfonas/efeitos adversos , Resultado do TratamentoRESUMO
The skin of the perianal region is very thin and sensitive. The carbon dioxide laser is a very effective tool for removing tumors and treating conditions of this area. It offers a "no touch" method of treatment for conditions of the perianal region. There is less bleeding, less pain, less swelling with the use of the carbon dioxide laser. The carbon dioxide laser is an effective tool for excising perianal tumors, rectal tumors, performing anal sacculectomies and treating perianal fistulas.
