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1.
Micromachines (Basel) ; 14(1)2022 Dec 26.
Artigo em Inglês | MEDLINE | ID: mdl-36677125

RESUMO

Traveling wave rotary ultrasonic motors (TRUMs) are widely used in various industrial processes due to their attractive features, such as compact structure, high accuracy, and fast response. However, the major limiting factors of the operational performance of TRUMs under high-voltage excitation are the nonlinear behavior caused by the nonlinearities of the piezoelectric materials and the friction between the stator and rotor of the motor. In this study, a nonlinear dynamics model and an identification method are presented to directly design the driver circuit for suppressing the nonlinear behavior under high voltage excitation. Firstly, by studying the time-frequency characteristics of the isolated electrode voltage, a single-sided Hertzian contact forced oscillator model of TRUMs is established, involving the nonlinearities of the piezoelectric material and friction. Secondly, a harmonic balance nonlinear identification is proposed in the time domain for TRUMs. The influence of the voltage and preload on the nonlinear phenomena is discussed. Lastly, a novel driver circuit is proposed to suppress the nonlinearities using feedback from the isolated electrode. Experiments showed that the total harmonic distortion decreased by 89.4% under 500 Vpp. The proposed drive circuit design method is used to find a high excitation voltage and preload to achieve greater motor output power.

2.
Med Phys ; 40(10): 101915, 2013 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24089917

RESUMO

PURPOSE: To measure and investigate the improvement of microcalcification (MC) visibility in cone beam breast CT with a high pitch (75 µm), thick (500 µm) scintillator CMOS/CsI flat panel detector (Dexela 2923, Perkin Elmer). METHODS: Aluminum wires and calcium carbonate grains of various sizes were embedded in a paraffin cylinder to simulate imaging of calcifications in a breast. Phantoms were imaged with a benchtop experimental cone beam CT system at various exposure levels. In addition to the Dexela detector, a high pitch (50 µm), thin (150 µm) scintillator CMOS/CsI flat panel detector (C7921CA-09, Hamamatsu Corporation, Hamamatsu City, Japan) and a widely used low pitch (194 µm), thick (600 µm) scintillator aSi/CsI flat panel detector (PaxScan 4030CB, Varian Medical Systems) were also used in scanning for comparison. The images were independently reviewed by six readers (imaging physicists). The MC visibility was quantified as the fraction of visible MCs and measured as a function of the estimated mean glandular dose (MGD) level for various MC sizes and detectors. The modulation transfer functions (MTFs) and detective quantum efficiencies (DQEs) were also measured and compared for the three detectors used. RESULTS: The authors have demonstrated that the use of a high pitch (75 µm) CMOS detector coupled with a thick (500 µm) CsI scintillator helped make the smaller 150-160, 160-180, and 180-200 µm MC groups more visible at MGDs up to 10.8, 9, and 10.8 mGy, respectively. It also made the larger 200-212 and 212-224 µm MC groups more visible at MGDs up to 7.2 mGy. No performance improvement was observed for 224-250 µm or larger size groups. With the higher spatial resolution of the Dexela detector based system, the apparent dimensions and shapes of MCs were more accurately rendered. The results show that with the aforementioned detector, a 73% visibility could be achieved in imaging 160-180 µm MCs as compared to 28% visibility achieved by the low pitch (194 µm) aSi/CsI flat panel detector. The measurements confirm that the Hamamatsu detector has the highest MTF, followed by the Dexel detector, and then the Varian detector. However, the Dexela detector, with its thick (500 µm) CsI scintillator and low noise level, has the highest DQE at all frequencies, followed by the Varian detector, and then the Hamamatsu detector. The findings on the MC visibility correlated well with the differences in MTFs, noise power spectra, and DQEs measured for these three detectors. CONCLUSIONS: The authors have demonstrated that the use of the CMOS type Dexela detector with its high pitch (75 µm) and thick (500 µm) CsI scintillator could help improve the MC visibility. However, the improvement depended on the exposure level and the MC size. For imaging larger MCs or scanning at high exposure levels, there was little advantage in using the Dexela detector as compared to the aSi type Varian detector. These findings correlate well with the higher measured DQEs of the Dexela detector, especially at higher frequencies.


Assuntos
Calcinose/diagnóstico por imagem , Tomografia Computadorizada de Feixe Cônico/instrumentação , Mamografia/instrumentação , Contagem de Cintilação/instrumentação , Imagens de Fantasmas
3.
Med Phys ; 38(12): 6429-42, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22149826

RESUMO

PURPOSE: In this study, we used a small field high resolution detector in conjunction with a full field flat panel detector to implement and investigate the dual detector volume-of-interest (VOI) cone beam breast computed tomography (CBCT) technique on a bench-top system. The potential of using this technique to image small calcifications without increasing the overall dose to the breast was demonstrated. Significant reduction of scatter components in the high resolution projection image data of the VOI was also shown. METHODS: With the regular flat panel based CBCT technique, exposures were made at 80 kVp to generate an air kerma of 6 mGys at the isocenter. With the dual detector VOI CBCT technique, a high resolution small field CMOS detector was used to scan a cylindrical VOI (2.5 cm in diameter and height, 4.5 cm off-center) with collimated x-rays at four times of regular exposure level. A flat panel detector was used for full field scan with low x-ray exposures at half of the regular exposure level. The low exposure full field image data were used to fill in the truncated space in the VOI scan data and generate a complete projection image set. The Feldkamp-Davis-Kress (FDK) filtered backprojection algorithm was used to reconstruct high resolution images for the VOI. Two scanning techniques, one breast centered and the other VOI centered, were implemented and investigated. Paraffin cylinders with embedded thin aluminum (Al) wires were imaged and used in conjunction with optically stimulated luminescence (OSL) dose measurements to demonstrate the ability of this technique to image small calcifications without increasing the mean glandular dose (MGD). RESULTS: Using exposures that produce an air kerma of 6 mGys at the isocenter, the regular CBCT technique was able to resolve the cross-sections of Al wires as thin as 254 µm in diameter in the phantom. For the specific VOI studied, by increasing the exposure level by a factor of 4 for the VOI scan and reducing the exposure level by a factor of 2 for the full filed scan, the dual-detector CBCT technique was able to resolve the cross-sections of Al wires as thin as 152 µm in diameter. The CNR evaluated for the entire Al wire cross-section was found to be improved from 5.5 in regular CBCT to 14.4 and 16.8 with the breast centered and VOI centered scanning techniques, respectively. Even inside VOI center, the VOI scan resulted in significant dose saving with the dose reduced by a factor of 1.6 at the VOI center. Dose saving outside the VOI was substantial with the dose reduced by a factor of 7.3 and 7.8 at the breast center for the breast centered and VOI centered scans, respectively, when compared to full field scan at the same exposure level. The differences between the two dual detector techniques in terms of dose saving and scatter reduction were small with VOI scan at 4× exposure level and full field scan at 0.5 × exposure level. The MGDs were only 94% of that from the regular CBCT scan. CONCLUSIONS: For the specific VOI studied, the dual detector VOI CBCT technique has the potential to provide high quality images inside the VOI with MGD similar to or even lower than that of full field breast CBCT. It was also found that our results were compromised by the use of inadequate detectors for the VOI scan. An appropriately selected detector would better optimize the image quality improvement that can be achieved with the VOI CBCT technique.


Assuntos
Neoplasias da Mama/diagnóstico por imagem , Tomografia Computadorizada de Feixe Cônico/instrumentação , Imageamento Tridimensional/métodos , Mamografia/instrumentação , Intensificação de Imagem Radiográfica/instrumentação , Interpretação de Imagem Radiográfica Assistida por Computador/instrumentação , Tomografia Computadorizada por Raios X/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Feminino , Humanos , Imagens de Fantasmas , Projetos Piloto , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Transdutores
4.
Med Phys ; 38(12): 6489-501, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22149832

RESUMO

PURPOSE: The scan equalization digital mammography (SEDM) technique combines slot scanning and exposure equalization to improve low-contrast performance of digital mammography in dense tissue areas. In this study, full-field digital mammography (FFDM) images of an anthropomorphic breast phantom acquired with an anti-scatter grid at various exposure levels were superimposed to simulate SEDM images and investigate the improvement of low-contrast performance as quantified by primary signal-to-noise ratios (PSNRs). METHODS: We imaged an anthropomorphic breast phantom (Gammex 169 "Rachel," Gammex RMI, Middleton, WI) at various exposure levels using a FFDM system (Senographe 2000D, GE Medical Systems, Milwaukee, WI). The exposure equalization factors were computed based on a standard FFDM image acquired in the automatic exposure control (AEC) mode. The equalized image was simulated and constructed by superimposing a selected set of FFDM images acquired at 2, 1, 1/2, 1/4, 1/8, 1/16, and 1/32 times of exposure levels to the standard AEC timed technique (125 mAs) using the equalization factors computed for each region. Finally, the equalized image was renormalized regionally with the exposure equalization factors to result in an appearance similar to that with standard digital mammography. Two sets of FFDM images were acquired to allow for two identically, but independently, formed equalized images to be subtracted from each other to estimate the noise levels. Similarly, two identically but independently acquired standard FFDM images were subtracted to estimate the noise levels. Corrections were applied to remove the excess system noise accumulated during image superimposition in forming the equalized image. PSNRs over the compressed area of breast phantom were computed and used to quantitatively study the effects of exposure equalization on low-contrast performance in digital mammography. RESULTS: We found that the highest achievable PSNR improvement factor was 1.89 for the anthropomorphic breast phantom used in this study. The overall PSNRs were measured to be 79.6 for the FFDM imaging and 107.6 for the simulated SEDM imaging on average in the compressed area of breast phantom, resulting in an average improvement of PSNR by ∼35% with exposure equalization. We also found that the PSNRs appeared to be largely uniform with exposure equalization, and the standard deviations of PSNRs were estimated to be 10.3 and 7.9 for the FFDM imaging and the simulated SEDM imaging, respectively. The average glandular dose for SEDM was estimated to be 212.5 mrad, ∼34% lower than that of standard AEC-timed FFDM (323.8 mrad) as a result of exposure equalization for the entire breast phantom. CONCLUSIONS: Exposure equalization was found to substantially improve image PSNRs in dense tissue regions and result in more uniform image PSNRs. This improvement may lead to better low-contrast performance in detecting and visualizing soft tissue masses and micro-calcifications in dense tissue areas for breast imaging tasks.


Assuntos
Algoritmos , Neoplasias da Mama/diagnóstico por imagem , Mamografia/métodos , Intensificação de Imagem Radiográfica/métodos , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Feminino , Humanos , Mamografia/instrumentação , Imagens de Fantasmas , Intensificação de Imagem Radiográfica/instrumentação , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Razão Sinal-Ruído
5.
Med Phys ; 38(2): 589-97, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21452696

RESUMO

PURPOSE: In this article, we describe a method to estimate the spatial dose variation, average dose and mean glandular dose (MGD) for a real breast using Monte Carlo simulation based on cone beam breast computed tomography (CBBCT) images. We present and discuss the dose estimation results for 19 mastectomy breast specimens, 4 homogeneous breast models, 6 ellipsoidal phantoms, and 6 cylindrical phantoms. METHODS: To validate the Monte Carlo method for dose estimation in CBBCT, we compared the Monte Carlo dose estimates with the thermoluminescent dosimeter measurements at various radial positions in two polycarbonate cylinders (11- and 15-cm in diameter). Cone-beam computed tomography (CBCT) images of 19 mastectomy breast specimens, obtained with a bench-top experimental scanner, were segmented and used to construct 19 structured breast models. Monte Carlo simulation of CBBCT with these models was performed and used to estimate the point doses, average doses, and mean glandular doses for unit open air exposure at the iso-center. Mass based glandularity values were computed and used to investigate their effects on the average doses as well as the mean glandular doses. Average doses for 4 homogeneous breast models were estimated and compared to those of the corresponding structured breast models to investigate the effect of tissue structures. Average doses for ellipsoidal and cylindrical digital phantoms of identical diameter and height were also estimated for various glandularity values and compared with those for the structured breast models. RESULTS: The absorbed dose maps for structured breast models show that doses in the glandular tissue were higher than those in the nearby adipose tissue. Estimated average doses for the homogeneous breast models were almost identical to those for the structured breast models (p=1). Normalized average doses estimated for the ellipsoidal phantoms were similar to those for the structured breast models (root mean square (rms) percentage difference = 1.7%; p = 0.01), whereas those for the cylindrical phantoms were significantly lower (rms percentage difference = 7.7%; p < 0.01). Normalized MGDs were found to decrease with increasing glandularity. CONCLUSIONS: Our results indicate that it is sufficient to use homogeneous breast models derived from CBCT generated structured breast models to estimate the average dose. This investigation also shows that ellipsoidal digital phantoms of similar dimensions (diameter and height) and glandularity to actual breasts may be used to represent a real breast to estimate the average breast dose with Monte Carlo simulation. We have also successfully demonstrated the use of structured breast models to estimate the true MGDs and shown that the normalized MGDs decreased with the glandularity as previously reported by other researchers for CBBCT or mammography.


Assuntos
Mama , Tomografia Computadorizada de Feixe Cônico/métodos , Mamografia/métodos , Método de Monte Carlo , Doses de Radiação , Mama/citologia , Humanos , Imagens de Fantasmas , Reprodutibilidade dos Testes
6.
Phys Med Biol ; 54(22): 6959-78, 2009 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-19887717

RESUMO

It is well recognized in projection radiography that low-contrast detectability suffers in heavily attenuating regions due to excessively low x-ray fluence to the image receptor and higher noise levels. Exposure equalization can improve image quality by increasing the x-ray exposure to heavily attenuating regions, resulting in a more uniform distribution of exposure to the detector. Image quality is also expected to be improved by using the slot-scan geometry to reject scattered radiation effectively without degrading primary x-rays. This paper describes the design of a prototype scan equalization digital radiography (SEDR) system implemented with an amorphous silicon (a-Si) thin-film transistor (TFT) array-based flat-panel detector. With this system, slot-scan geometry with alternate line erasure and readout (ALER) technique was used to achieve scatter rejection. A seven-segment beam height modulator assembly was mounted onto the fore collimator to regulate exposure regionally for chest radiography. The beam modulator assembly, consisting of micro linear motors, lead screw cartridge with lead (Pb) beam blockers attached, position feedback sensors and motor driver circuitry, has been tested and found to have an acceptable response for exposure equalization in chest radiography. An anthropomorphic chest phantom was imaged in the posterior-anterior (PA) view under clinical conditions. Scatter component, primary x-rays, scatter-to-primary ratios (SPRs) and primary signal-to-noise ratios (PSNRs) were measured in the SEDR images to evaluate the rejection and redistribution of scattered radiation, and compared with those for conventional full-field imaging with and without anti-scatter grid methods. SPR reduction ratios (SPRRRs, defined as the differences between the non-grid full-field SPRs and the reduced SPRs divided by the former) yielded approximately 59% for the full-field imaging with grid and 82% for the SEDR technique in the lungs, and 77% for the full-field imaging with grid and 95% for the SEDR technique in the subdiaphragm. The SEDR technique demonstrated a substantial improvement in PSNRs over the anti-scatter grid technique. The improvements of PSNRs varied with the regions and are more pronounced in heavily attenuating regions.


Assuntos
Intensificação de Imagem Radiográfica/instrumentação , Ecrans Intensificadores para Raios X , Desenho Assistido por Computador , Desenho de Equipamento , Análise de Falha de Equipamento , Reprodutibilidade dos Testes , Selênio , Sensibilidade e Especificidade
7.
Phys Med Biol ; 54(21): 6691-709, 2009 Nov 07.
Artigo em Inglês | MEDLINE | ID: mdl-19841514

RESUMO

With volume-of-interest (VOI) cone-beam computed tomography (CBCT) imaging, one set of projection images are acquired with the VOI collimator at a regular or high exposure level and the second set of projection images are acquired without the collimator at a reduced exposure level. The high exposure VOI scan data inside the VOI and the low exposure full-field scan data outside the VOI are then combined together to generate composite projection images for image reconstruction. To investigate and quantify scatter reduction, dose saving and image quality improvement in VOI CBCT imaging, a flat panel detector-based bench-top experimental CBCT system was built to measure the dose, the scatter-to-primary ratio (SPR), the image contrast, noise level, the contrast-to-noise ratio (CNR) and the figure of merit (FOM) in the CBCT reconstructed images for two polycarbonate cylinders simulating the small and the large phantoms. The results showed that, compared to the full field CBCT technique, radiation doses for the VOI CBCT technique were reduced by a factor of 1.20 and 1.36 for the small and the large phantoms at the phantom center, respectively, and from 2.7 to 3.0 on the edge of the phantom, respectively. Inside the VOI, the SPRs were substantially reduced by a factor of 6.6 and 10.3 for the small and the large phantoms, the contrast signals were improved by a factor of 1.35 and 1.8, and the noise levels were increased by a factor of 1.27 and 1.6, respectively. As a result, the CNRs were improved by a factor of 1.06 and 1.13 for the small and the large phantoms and the FOM improved by a factor of 1.4 and 1.7, respectively.


Assuntos
Espalhamento de Radiação , Tomografia Computadorizada por Raios X/métodos , Algoritmos , Mama/patologia , Neoplasias da Mama/radioterapia , Calibragem , Desenho de Equipamento , Feminino , Humanos , Mamografia/métodos , Modelos Estatísticos , Método de Monte Carlo , Imagens de Fantasmas , Planejamento da Radioterapia Assistida por Computador/métodos , Raios X
8.
Med Phys ; 36(9): 4007-14, 2009 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-19810473

RESUMO

PURPOSE: In this study, the authors investigated the feasibility of a dual resolution volume-of-interest (VOI) cone beam breast CT technique and compared two implementation approaches in terms of dose saving and scatter reduction. METHODS: With this technique, a lead VOI mask with an opening is inserted between the x-ray source and the breast to deliver x-ray exposure to the VOI while blocking x rays outside the VOI. A CCD detector is used to collect the high resolution projection data of the VOI. Low resolution cone beam CT (CBCT) images of the entire breast, acquired with a flat panel (FP) detector, were used to calculate the projection data outside the VOI with the ray-tracing reprojection method. The Feldkamp-Davis-Kress filtered backprojection algorithm was used to reconstruct the dual resolution 3D images. Breast phantoms with 180 microm and smaller microcalcifications (MCs) were imaged with both FP and FP-CCD dual resolution CBCT systems, respectively. Two approaches of implementing the dual resolution technique, breast-centered approach and VOI-centered approach, were investigated and evaluated for dose saving and scatter reduction with Monte Carlo simulation using a GEANT4 package. RESULTS: The results showed that the breast-centered approach saved more breast absorbed dose than did VOI-centered approach with similar scatter reduction. The MCs in fatty breast phantom, which were invisible with FP CBCT scan, became visible with the FP-CCD dual resolution CBCT scan. CONCLUSIONS: These results indicate potential improvement of the image quality inside the VOI with reduced breast dose both inside and outside the VOI.


Assuntos
Neoplasias da Mama/diagnóstico por imagem , Tomografia Computadorizada de Feixe Cônico/métodos , Mamografia/métodos , Algoritmos , Mama/efeitos da radiação , Calcinose/diagnóstico por imagem , Simulação por Computador , Estudos de Viabilidade , Feminino , Humanos , Imageamento Tridimensional/métodos , Método de Monte Carlo , Parafina/química , Imagens de Fantasmas , Doses de Radiação , Espalhamento de Radiação , Software , Raios X
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