RESUMO
Objective: To observe the application value of apical vertical angle and ejection velocity in diagnosis of apical hypertrophic cardiomyopathy (AHCM). Methods: A total of 51 patients with AHCM, including 30 typical AHCM (T-AHCM group) and 21 pre-AHCM (P-AHCM group) were enrolled. Forty matched healthy volunteers and 44 hypertensives were recruited as normal control (NC group) and hypertension group (HT group), respectively. Echocardiographic studies were performed in all subjects to acquire and analyze apical vertical angle (θap) and its systolic rate of change (△θap) in end diastolic and end systolic stage, peak ejection velocity (Vap) in systolic stage and its ratio to the velocity in left ventricular outflow tract (VLVOT). Results: Compared with NC and HT groups, θap decreased and △θap and Vap increased significantly in both P-AHCM and T-AHCM groups (all P<0.001). Conclusion: Decreased apical vertical angle and systolic rate of angle change and local ejection velocity are found in patients with AHCM even in early stage. Combination of these indicators with specific ECG changes are expected to improve the detection rate of AHCM with ultrasound.
