Diagnosis research of Helicobacter pylori negative duodenal ulcer / 中国医师进修杂志

Objective To investigate the diagnosis methods of Helicobacter pylori (Hp) negative duodenal ulcer,to provide clinical analysis for diagnosing Hp negative duodenal ulcer.Methods Reviewed 140 patients with duodenal ulcer who treated from January 2010 to January 2013.Adopted different detection methods of Hp negative diagnosis.Results In 140 patients,Hp positive was 90 cases(64.3％,90/140) and Hp negative was 50 cases (35.7％,50/140).Pathology examination negative was 30 cases (2 1.4％,30/1 40),13C breath test negative was 35 cases (25.0％,35/140),the invasive methods based on pathology examination and 13C breath test negative was 40 cases (28.6％,40/140).Conclusion The diagnosis of Hp negative duodenal ulcer is more complex,need comprehensive factors,to exclude various possibility of false negative.

The Anesthesia Gastroscopy Used in Aged-patients Over 80 Years Old / 医学研究杂志

Objective To study the feasibility and safety for using anesthesia gastroscopy in aged-patients over 80 years old.Methods Selecting 84 cases of aged-patients over 80 years old as anesthesia group(group 1),22 cases of aged-patients over 80 years old as normal gastroscopy group(group 2)and 100 cases of young-middle age as anesthesia control group(group 3).Low dose propofol and fentanyl combined atropine were injected into venous in anesthesia gastroscopy.The BP,HR,SpO2,patients reactions during gastroscopy,stomach peristalsis rates,awake time were detected before,during and after gastroscopy.Results Patients in group 1 felt much less discomfortable than those in group 2.Anesthesia group felt much satisfactorily than normal gastroscopy group.The BP,HR,SpO2 in group 1 were decreased transitorily during examination and resumed rapidly after examination.There were no severe complications in anesthesia gastroscopy.However,the BP and HR were increased obviously in normal gastroscopy group.The dosage of propofol in group 1 was much less than that in group 3.Conclusions The use of anesthesia gastroscopy with low dose propofol and fentanyl combined atropine intravenously in aged-patients over 80 years old is safe and comfortable.