Repeated pregnancies in patients with non-immunoglobulin a mesangioproliferative glomerulonephritis.

AIM: To analyze the effect of repeated pregnancies on underlying MesGN and see the reciprocal effect on maternal and fetal outcome. PATIENTS AND METHODS: Pregnancy records of cases with histological diagnosis of MesGN were reviewed, and past medical histories recorded. RESULTS: Cesarean section (CS). Only two patients developed renal insufficiency after undergoing 5 and 11 pregnancies and follow-up of 9 and 20 years respectively. CONCLUSION: The outcome of repeated pregnancies in patients with MesGN is comparable to normal deliveries. A higher incidence of pre-eclampsia, LBW babies and CS was noted in the post- compared to the pre-MesGN pregnancies. Repeated pregnancies do not influence the course of the MesGN.

Renal cell carcinoma of contralateral kidney with secondaries in gallbladder eight years after nephrectomy.

A 55-year-old female underwent right nephrectomy for renal cell carcinoma (RCC). The histopathology showed clear cell carcinoma. There was no evidence of metastasis. After remaining asymptomatic for eight years, she developed pain in the right loin. Abdominal ultrasound, computerized tomography (CT) Scan and magnetic resonance imaging (MRI) were suggestive of a tumor mass in the right renal area, multiple tumor masses in the left kidney and a mass in the gallbladder. Cholecystectomy, left radical nephrectomy and right adrenal mass with excision of adjacent lymph nodes were performed. The histopathology from all sites was suggestive of RCC. She was maintained on hemodialysis. Two and half years later she died after surgical exploration for spinal cord decompression due to metastasis to the dorsal spine.