RESUMO
The article presents analysis of legal regulation of medical technologies in Russia. The proper development of medicine and health care is impossible without permanent improvement and implementation of new medical technologies. The upcoming decades will be an era of development of bio-technologies, cellular and gene technologies included. The proposed analysis is focused on conceptual set, analysis of actual normative legal base regulating mentioned relationships and identification of perspectives of development of medical technologies. The adequate and competent legal regulation creates enabling environment developing new technological capabilities. The legislation should avoid inhibiting retributive mode and apply particularly permitting and regulating approach determining framework not to be violated. Undoubtedly, these activities should be carried out in conjunction with professional medical community to develop legislation ensuring the highest possible level of development of health care practice.
Assuntos
Atenção à Saúde , Federação RussaRESUMO
A 100 MeV eight-turn accelerator-recuperator intended to drive a high-power infrared free-electron laser (FEL) is currently under construction in Novosibirsk. The first stage of the machine includes a one-turn accelerator-recuperator that contains a full-scale RF system. It was commissioned successfully in June 2002.
RESUMO
It is established that clofelin suppresses the human and dog insulin gastric secretion as well as human basal and histamine secretion. Clofelin has no effect on the secretory function of the dog stomach, stimulated by pentagastrin, carbachol histamine. It is supposed that clofelin-induced suppression of the human histamine gastric secretion takes place due to the inhibition of basal secretory component being a part of the common secretory effect on histamine. Clofelin may be promising drug in the treatment of patients with hypertension and duodenum ulcer.
Assuntos
Clonidina/farmacologia , Mucosa Gástrica/efeitos dos fármacos , Adolescente , Adulto , Animais , Cães , Interações Medicamentosas , Jejum/fisiologia , Suco Gástrico/efeitos dos fármacos , Suco Gástrico/metabolismo , Mucosa Gástrica/metabolismo , Humanos , Pessoa de Meia-Idade , Especificidade da Espécie , Fatores de TempoRESUMO
The time course of the levels of glycemia, gastric secretion of acid and pepsin, and indices of variation pulsometry in response to intravenous injection of glucose (0.66 g/kg) was studied in 42 patients with duodenal ulcer and in 11 healthy persons. It was established that in duodenal ulcer the reactivity of the central glucoreceptor mechanism regulating acid and pepsin secretion, was considerably elevated, especially in patients with complicated forms of disease and gastric hypersecretion. A hyperglycemia-induced degree of acid and pepsin secretion suppression was 1.5- 2-fold higher in the study group than in the control group. The authors proposed that the ratio of a degree of a decrease in acid production (delta % AP) and pepsin production (delta % PP) to the level of glycemia increment (delta % Gl)--acid-glucose (delta % AP/delta % Gl) and pepsin-glucose (delta % PP/delta % Gl) indices should be calculated for overall assessment of a reaction to hyperglycemia of the hypothalamic glucose sensitive mechanism of gastric secretion regulation. These indices reflected a degree of hypothalamic dysfunctions and could serve as markers of the gravity of disease. In the patients with uncomplicated duodenal ulcer as compared to the control group, the acid-glucose index was 2.6-fold and the pepsin-glucose index 1.6-fold higher, and in the patients with complicated duodenal ulcer the indices were 4.6- and 2.9-fold higher, respectively; the indices were higher in the patients with basal acid hypersecretion and hyperplasia of parietal cells.
