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1.
Phytother Res ; 36(1): 62-72, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34528300

RESUMO

With increased popular awareness of food safety and environmental protection, plant essential oil has attracted interest due to the absence of residue, its high efficiency, antioxidant, immune regulation, antibacterial, insecticidal, and other advantages. Their application in degradation and elimination of mycotoxin toxicity has attracted increasing attention. This paper reviews the structure, antibacterial activity, antibacterial mechanism, and toxic effects of essential oils. The inhibitory effects of various essential oils on different mycotoxins were studied. The research progress on the inhibitory effects of plant essential oils on fungi and mycotoxins in recent years was summarized to provide reference for the application of plant essential oils.


Assuntos
Micotoxinas , Óleos Voláteis , Antifúngicos/farmacologia , Fungos , Óleos Voláteis/farmacologia , Óleos de Plantas/farmacologia
2.
Molecules ; 26(17)2021 Aug 29.
Artigo em Inglês | MEDLINE | ID: mdl-34500671

RESUMO

Fumonisin B1 (FB1), belonging to the member of fumonisins, is one of the most toxic mycotoxins produced mainly by Fusarium proliferatum and Fusarium verticillioide. FB1 has caused extensive contamination worldwide, mainly in corn, rice, wheat, and their products, while it also poses a health risk and is toxic to animals and human. It has been shown to cause oxidative stress, endoplasmic reticulum stress, cellular autophagy, and apoptosis. This review focuses on the current stage of FB1 contamination, its toxic effects of acute toxicity, immunotoxicity, organ toxicity, and reproductive toxicity on animals and humans. The potential toxic mechanisms of FB1 are discussed. One of the main aims of the work is to provide a reliable reference strategy for understanding the occurrence and toxicity of FB1.


Assuntos
Fumonisinas/análise , Animais , Apoptose/efeitos dos fármacos , Autofagia/efeitos dos fármacos , Fumonisinas/farmacologia , Fusarium/química , Humanos
3.
Curr Microbiol ; 78(10): 3597-3608, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34350485

RESUMO

As the main pathogen threatening human and animal health, viruses can affect the immunity and metabolism of bodies. There are innate microbial barriers in the digestive tract of the body to preserve the homeostasis of the animal body, which directly or indirectly influences the host defence against viral infection. Understanding the interaction between viruses and intestinal microbiota or probiotics is helpful to study the pathogenesis of diseases. Here, we review recent studies on the interaction mechanism between intestinal microbiota and viruses. The interaction can be divided into two aspects: inhibition of viral infection by microbiota and promotion of viral infection by microbiota. The treatment of viral infection by probiotics is summarized.


Assuntos
Microbioma Gastrointestinal , Microbiota , Probióticos , Vírus , Animais , Trato Gastrointestinal , Humanos
4.
Molecules ; 26(11)2021 Jun 05.
Artigo em Inglês | MEDLINE | ID: mdl-34198909

RESUMO

Harmful fungi in nature not only cause diseases in plants, but also fungal infection and poisoning when people and animals eat food derived from crops contaminated with them. Unfortunately, such fungi are becoming increasingly more resistant to traditional synthetic antifungal drugs, which can make prevention and control work increasingly more difficult to achieve. This means they are potentially very harmful to human health and lifestyle. Antifungal peptides are natural substances produced by organisms to defend themselves against harmful fungi. As a result, they have become an important research object to help deal with harmful fungi and overcome their drug resistance. Moreover, they are expected to be developed into new therapeutic drugs against drug-resistant fungi in clinical application. This review focuses on antifungal peptides that have been isolated from bacteria, fungi, and other microorganisms to date. Their antifungal activity and factors affecting it are outlined in terms of their antibacterial spectra and effects. The toxic effects of the antifungal peptides and their common solutions are mentioned. The mechanisms of action of the antifungal peptides are described according to their action pathways. The work provides a useful reference for further clinical research and the development of safe antifungal drugs that have high efficiencies and broad application spectra.


Assuntos
Antifúngicos/farmacologia , Peptídeos Catiônicos Antimicrobianos/farmacologia , Micoses/prevenção & controle , Doenças das Plantas/prevenção & controle , Animais , Antifúngicos/farmacocinética , Peptídeos Catiônicos Antimicrobianos/farmacocinética , Desenvolvimento de Medicamentos , Farmacorresistência Fúngica Múltipla/efeitos dos fármacos , Estabilidade de Medicamentos , Humanos
5.
Small ; 16(40): e2004126, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32876996

RESUMO

Recently, all-inorganic halide perovskite (CsPbX3 , (X = Cl, Br, and I)) nanocrystals (NCs) based hybrid architectures have attracted extensive attention owing to their distinct luminescence characteristics. However, due to stress and lattice mismatch, it is still a challenge to construct heterojunctions between perovskite NCs and the nanostructures with different lattice parameters and non-cubic contour. In this work, a room temperature mechanochemical method is presented to construct TiO2 @CsPbBr3 hybrid architectures, in which TiO2 nanoparticles (NPs) with a hard lattice as nano "balls" mill off the angles and anchor to the CsPbBr3 NCs with a soft lattice. On the contrary, to ball-mill without TiO2 or with conventional ceramics balls replacing TiO2 , CsPbBr3 NCs still maintain cubic contour deriving from their cubic crystal structures. Moreover, the TiO2 @CsPbBr3 architectures display distinct improvement of photoluminescence quantum yields and more excellent thermal stability in contrast with pristine CsPbBr3 owing to the passivation of surface defect, small surface area, and energy transfer from CsPbBr3 to TiO2 . Meanwhile, there is distinct luminous decay characteristic under the radiation of UV and visible light due to the "on" and "off" TiO2 response. The method provides an alternative strategy to acquire other anchoring heterojunctions based on perovskite NCs for further regulating their luminescent characteristics.

6.
Nanomaterials (Basel) ; 10(6)2020 Jun 13.
Artigo em Inglês | MEDLINE | ID: mdl-32545772

RESUMO

In this work, the compositional optimization in copper oxide/tungsten trioxide (CuO/WO3) composites was systematically studied for hydrogen sulfide (H2S) sensing. The response of CuO/WO3 composites changes from p-type to n-type as the CuO content decreases. Furthermore, the p-type response weakens while the n-type response strengthens as the Cu/W molar ratio decreases from 1:0 to 1:10. The optimal Cu/W molar ratio is 1:10, at which the sensor presents the ultrahigh n-type response of 1.19 × 105 to 20 ppm H2S gas at 40 °C. Once the temperature rises from 40 °C to 250 °C, the CuO/WO3 (1:1) sensor presents the p-n response transformation, and the CuO/WO3 (1:1.5) sensor changes from no response to n-type response, because the increased temperature facilitates the Cu-S bonds break and weakens the p-type CuO contribution to the total response, such that the CuS bond decomposition by a thermal effect was verified by a Raman analysis. In addition, with a decrease in CuO content, the CuO is transformed from partly to completely converting to CuS, causing the resistance of CuO to decrease from increasing and, hence, a weakening mode of p-CuO and n-WO3 to the total response turns to a synergistic mode to it.

7.
Nanomaterials (Basel) ; 10(4)2020 Apr 17.
Artigo em Inglês | MEDLINE | ID: mdl-32316393

RESUMO

In this work, the high crystalline copper oxide (CuO) nanoparticles were fabricated by a hydrothermal method, and their structural properties were characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). The sensing results show that CuO nanoparticles exhibit enhanced sensitivity and good selectivity for hydrogen sulfide (H2S) gas at a low temperature. There are two working mechanisms involved in the H2S sensing based on CuO nanoparticle sensors. They are the H2S oxidation mechanism and the copper sulphide (CuS) formation mechanism, respectively. The two sensing mechanisms collectively enhance the sensor's response in the H2S sensing process. The Cu-S bonding is stable and cannot break spontaneously at a low temperature. Therefore, the CuS formation inhibits the sensor's recovery process. Such inhibition gradually enhances as the gas concentration increases from 0.2 ppm to 5 ppm, and it becomes weaker as the operating temperature rises from 40 °C to 250 °C. The XPS results confirmed the CuS formation phenomenon, and the micro Raman spectra demonstrated that the formation of CuS bonding and its decomposition can be effectively triggered by a thermal effect. Gas-sensing mechanism analysis supplied abundant cognition for the H2S sensing phenomena based on CuO materials.

8.
Nanoscale ; 11(15): 7287-7292, 2019 Apr 11.
Artigo em Inglês | MEDLINE | ID: mdl-30933201

RESUMO

Herein, we synthesized and extracted pure semiconducting single-walled carbon nanotubes (s-SWCNTs). Moreover, the nonlinear optical (NLO) properties, such as saturable absorption, two-photon absorption coefficient, modulation depth and optical limitation, of s-SWCNTs were experimentally determined using a high-energy 1064 nm nanosecond (ns) laser. Compared with the common SWCNTs, the s-SWCNTs demonstrated lower saturation intensity and lower two-photon absorption (TPA) coefficient. The modulation depth of the s-SWCNTs was as high as 8.6%. Based on these parameters, the s-SWCNTs can be used as excellent saturable absorbers in pulsed laser applications.

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