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1.
Math Biosci Eng ; 18(4): 4127-4145, 2021 05 12.
Artigo em Inglês | MEDLINE | ID: mdl-34198429

RESUMO

Radio frequency energy harvesting (EH) technology can harvest the electromagnetic energy in the surrounding environment, and reduce the dependence of the communication devices on battery or power grid as power source, which is a very promising means of energy substitution and acquisition scheme. The random characteristics of wireless channel fading and possible co-channel interference (CCI) have great influence on EH efficiency and wireless communication performance with more complicated theoretical analysis. In this paper, the exact closed-form expressions of effective throughput of "harvest-store-use" and "harvest-use" multi-slot EH schemes with Rayleigh channel fading and CCI are derived theoretically. The simulation results show that in Rayleigh fading channels with CCI, CCI is beneficial to energy harvesting of EH device, but it will deteriorate the reception of required signals by information receiving device. Although there are obvious differences in working mechanism, working conditions and communication performance between the "harvest-store-use" scheme and the "harvest-use" scheme, the optimal time slot should be selected to balance the transmission probability and delay, minimize the interference of CCI to the desired signal, and improve the energy conversion efficiency of the energy harvester.


Assuntos
Redes de Comunicação de Computadores , Tecnologia sem Fio , Comunicação , Simulação por Computador , Probabilidade
2.
Sci Rep ; 9(1): 20024, 2019 12 27.
Artigo em Inglês | MEDLINE | ID: mdl-31882933

RESUMO

Bacterial vaginosis (BV) is a common condition among women of reproductive age. A sensitive, quantitative and rapid assay is needed for the diagnosis of and, particularly, therapy monitoring for BV. Bacterial sialidase appears to play an important role in bacterial biofilms on vaginal epithelium, a condition closely associated with BV. Here, we report a biochemiluminescent sialidase assay that uses a substrate derivatized with firefly luciferin. In the presence of sialidase in the reaction, the substrate is cleaved to release luciferin, which is subsequently oxidized by firefly luciferase to generate a light signal. Thus, the light signal intensity can be used to detect and measure the relative concentration of sialidase in a vaginal sample as a means of BV diagnosis. All reagents are present in a reagent bead and sample buffer, enabling essentially a one-step assay. The assay is highly sensitive and quantitative, with a sensitivity and specificity of 95.40% and 94.94%, respectively, compared to the Amsel method. Interestingly, only 27.6% of those with BV had high levels of sialidase activity with a signal to cutoff ratio of 10 or more. The assay may be used for diagnosis of BV, risk assessment of BV patients in terms of sialidase activity levels, and monitoring antibiotic therapy.


Assuntos
Neuraminidase/metabolismo , Vaginose Bacteriana/diagnóstico , Adulto , Feminino , Humanos , Luminescência , Pessoa de Meia-Idade , Sensibilidade e Especificidade , Especificidade por Substrato , Vaginose Bacteriana/microbiologia
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