High-power continuous-wave optical waveguiding in a silica micro/nanofibre.

As miniature fibre-optic platforms, micro/nanofibres (MNFs) taper-drawn from silica fibres have been widely studied for applications from optical sensing, nonlinear optics to optomechanics and atom optics. While continuous-wave (CW) optical waveguiding is frequently adopted, so far almost all MNFs are operated in low-power region (e.g., <0.1 W). Here, we demonstrate high-power low-loss CW optical waveguiding in MNFs around 1550-nm wavelength. We show that a pristine MNF, even with a diameter down to 410 nm, can waveguide an optical power higher than 10 W, which is about 30 times higher than demonstrated previously. Also, we predict an optical damage threshold of 70 W. In high-power CW waveguiding MNFs, we demonstrate high-speed optomechanical driving of microparticles in air, and second harmonic generation efficiency higher than those pumped by short pulses. Our results may pave a way towards high-power MNF optics, for both scientific research and technological applications.

Asymmetric Reflection Induced in Reciprocal Hyperbolic Materials.

Reflection is one of the most fundamental properties of light propagation. The ability to engineer this property can be a powerful tool when constructing a variety of now ubiquitous optical and electronic devices, including one-way mirrors and antennas. Here, we show from both experimental and theoretical evidence that highly asymmetric reflection can be induced in reciprocal hyperbolic materials. This asymmetry stems from the asymmetric cross-polarization conversion between two linearly polarized waves, an intrinsic and more exotic property of hyperbolic media that is bereft of research. In addition to angle-controllable reflection, our findings suggest that optical devices could utilize the polarization of the incident beam, or even the polarization of the output wave, to engineer functionality; additionally, in hyperbolic slabs or films, the asymmetry can be tailored by controlling the thickness of the material. Such phenomena are key for directional-dependent optical and optoelectronic devices.

Strong mode coupling-enabled hybrid photon-plasmon laser with a microfiber-coupled nanorod.

Laser based on single plasmonic nanoparticle can provide optical frequency radiation far beyond the diffraction limit and is one of the ultimate goals of nanolasers, yet it remains a challenge to be realized because of the inherently high Ohmic loss. Here, we report the direct observation of lasing in microfiber-coupled single plasmonic nanoparticles enabled by strong mode coupling. We show that, by strongly coupling a gold nanorod (GNR) with the whispering gallery cavity of a dye-doped polymer microfiber (with diameter down to 2.0 µm), the substantially enhanced optical coherence of the hybrid photon-plasmon mode and effective gain accumulated from the active microfiber cavity enable single-mode laser emission from the GNR at room temperature with a threshold as low as 2.71 MW/cm2 and a linewidth narrower than 2 nm.

Restorable Neutralization of Poly(acrylic acid) Binders toward Balanced Processing Properties and Cycling Performance for Silicon Anodes in Lithium-Ion Batteries.

Neutralization of poly(acrylic acid) (PAA)-based binders using lithium hydroxide is a common strategy for fabricating silicon anode laminates, which improves rheological properties of slurries toward high-quality electrode laminates. However, the significantly increased basicity causes degradation of Si particles while the irreversible conversion of carboxylic acid groups to lithium carboxylates undermines the binding strength, collectively leading to adverse cycling performance of the fabricated Si anodes. Herein, a novel neutralization process for PAA binders is developed. A weak base, ammonia (NH3), was discovered as a neutralizing agent that still promotes rheological response of binder solutions but results in a reduced pH increase. Interestingly, the resulting ammonium carboxylate groups may cleave during the drying process to restore the neutralized PAA (PAA-NH3) binders to their pristine states. The best-performing composition of 50% neutralization (PAA-50%NH3) provides comparable rheological response as a PAA-Li binder as well as much improved cycling performance. The half-cells using the PAA-50%NH3 binder can deliver 60% capacity retention over 100 cycles at C/3 rate, affording a 23.8% increase compared to PAA-Li half-cells. This restorable neutralization process of PAA binders represents an innovative strategy of mitigating issues from slurry processing of Si particles to achieve concurrent improvements in high-quality lamination and cycling performance.

Competitive Pi-Stacking and H-Bond Piling Increase Solubility of Heterocyclic Redoxmers.

Redoxmers are organic molecules that carry electric charge in flow batteries. In many instances, they consist of heteroaromatic moieties modified with appended groups to prevent stacking of the planar cores and increase solubility in liquid electrolytes. This higher solubility is desired as it potentially allows achieving greater energy density in the battery. However, the present synthetic strategies often yield bulky molecules with low molarity even when they are neat and still lower molarity in liquid solutions. Fortunately, there are exceptions to this rule. Here, we examine one well-studied redoxmer, 2,1,3-benzothiadiazole, which has solubility ∼5.7 M in acetonitrile at 25 °C. We show computationally and prove experimentally that the competition between two packing motifs, face-to-face π-stacking and random N-H bond piling, introduces frustration that confounds nucleation in crowded solutions. Our findings and examples from related systems suggest a complementary strategy for the molecular design of redoxmers for high energy density redox flow cells.

CdTe microwires as mid-infrared optical waveguides.

Cadmium telluride (CdTe) has been proven to be an attractive mid-infrared (MIR) material with a large refractive index (~2.68 at 4.5 µm) and broadband transparency (~1 to 25 µm). CdTe microwires (MWs) with diameters from a few to about ten micrometers were fabricated by a thermal evaporation process. MIR light was coupled into and guided through individual MWs. Excellent optical waveguiding properties of these MWs are experimentally obtained within MIR spectral range (up to 8.6 µm), with waveguiding losses from 1.3 to 13 dB/cm. Our results show that CdTe MWs can be used as wavelength or subwavelength-width waveguides for MIR microphotonics or circuits.

Enhancing the cellular anti-proliferation activity of pyridazinones as c-met inhibitors using docking analysis.

A series of 2, 6-disubstituted pyridazinone derivatives were evaluated and optimized for their c-Met inhibitory activity in enzyme and cellular assay. An analysis of the SAR results arising from computer modeling analysis of members of the library led to the proposal that in order to obtain optimal inhibitory activity in cellular systems the lipophilic/hydrophilic properties of individual structural fragments in the inhibitors need to match those of corresponding binding pockets in the enzyme. Guided by this proposal, the quinoline-pyridazinone 8a, containing hydrophobic 6-indolyl pyridazinone and quinoline moieties along with a hydrophilic morpholine terminal group, was designed and synthesized. The results of studies with this substance showed that it is a selective c-Met inhibitor with both a high enzyme inhibition IC50 value of 4.2 nM and a high EBC-1 cell proliferation inhibition IC50 value of 17 nM.

Discovery of novel 2,6-disubstituted pyridazinone derivatives as acetylcholinesterase inhibitors.

2,6-Disubstituted pyridazinone 4 was identified by HTS as a novel acetylcholinesterase (AChE) inhibitor. Under SAR development, compound 17e stood out as displaying high AChE inhibitory activity and AChE/butyrylcholinesterase (BuChE) selectivity in vitro. Docking studies revealed that 17e might interact with the catalytic active site (CAS) and the peripheral anionic site (PAS) simultaneously. Based on this novel binding information, 6-ortho-tolylamino and N-ethyl-N-isopropylacetamide substituted piperidine were disclosed as new PAS and CAS binders.