Arterial blood pressure and blood lipids as cardiovascular risk factors and occupational stress in Taiwan.

BACKGROUND: This study is to determine whether occupational stress (defined as high psychological demands and low decision latitude on the job) is associated with increased blood pressure and abnormal level of blood lipids as cardiovascular risk factors. METHODS: We conducted a cross-sectional study at three work sites of 526 white-collar male workers aged 20 to 66 years without evidence of cardiovascular disease. Systolic, diastolic blood pressure, serum total, high-density lipoprotein cholesterol and plasma triglyceride were measured. Occupational stress index was derived from data collected in the job strain questionnaire. RESULTS: In multiple linear regression models, occupational stress index was significantly related to diastolic blood pressure and plasma triglyceride, after adjusting for age, education, smoking, and alcohol consumption. A higher occupational stress index was directly associated with higher systolic, diastolic blood pressure and higher level of plasma triglyceride. CONCLUSIONS: These data from a white-collar working population confirm independent relations between occupational stress defined in the job demand-control model and diastolic blood pressure observed in predominantly Western populations and extend the range of associations to plasma triglyceride than do previous studies.

Estimating stature from knee height for adults in Taiwan.

BACKGROUND: Many of the indices utilized in the assessment of nutritional status are dependent upon stature. Knee height has been used to predict stature in western countries when standing height cannot be measured, however, an adequate stature-knee height equation has not been established for the population in Taiwan. METHODS: A total of 1179 healthy men (603) and women (576) were recruited from those who had undergone comprehensive check-ups at their own expense from March through August 1998 at Lin-Kou Chang-Gung Memorial Hospital, Taiwan. The subjects were freely ambulatory without kyphosis or scoliosis noted on their chest X-ray or KUB films. The automatic supersonic system was used to measure stature and body weight. A Ross caliper was used to measure recumbent left knee height. Multiple linear regression was used to obtain equations to estimate stature using knee height and age. RESULTS: Stature of adults highly correlated with their knee height (r = 0.73 with 95%CI between 0.69 and 0.77 for men, and r = 0.68 with 95%CI between 0.63 and 0.72 for women) but declined with age (men: r = -0.17 with 95%CI between -0.09 and -0.24; women: r = -0.22 with 95%CI between -0.14 and -0.29). Knee height changed very little with age in both genders. To predict stature, a linear regression model should include knee height and age as predictors to reach r2 as 0.61 and 0.58 for men and women, respectively. The stature-knee height equations were "stature = 85.10 + 1.73 x knee height -0.11 x age" for men, "stature = 91.45 + 1.53 x knee height -0.16 x age" for women. CONCLUSION: Our stature-knee height equations provided good predictions on stature of adult population in Taiwan, and was superior when compared with equations developed from other populations.

Evaluation of the hepatic and renal-protective effects of Ganoderma lucidum in mice.

The antioxidative effect of hot water extract of the mushroom Ganoderma lucidum on ethanol-induced free radical generation had been studied. In order to further investigate the hepatic and renal protective mechanism of Ganoderma lucidum, rates of lipid peroxidation were determined. The hot water extract of Ganoderma lucidum dose-dependently exhibited antioxidative effect on mouse liver and kidney lipid peroxidation; our results indicated that hepatic and renal homogenates have a higher malonic dialdehyde level in an ethanol administered group than in the Ganoderma lucidum treated group. It was concluded that the hepatic and renal protective mechanism of Ganoderma lucidum, might be due at least in part to its prominent superoxide scavenging effect. Ganoderma extract could protect the liver and kidney from superoxide induced hepatic and renal damages.

Investigation on subclinical aspects related to intestinal parasitic infections among Thai laborers in Taipei.

BACKGROUND: The migration of foreign workers from developing regions to developed countries may potentially lead to transmission of intestinal parasitic infections. In order to determine the relationship between intestinal parasitic infections and the health status of foreign workers, 302 Thai laborers brought to Taiwan were examined in this study. Nine species of parasites were found in 64.9% of laborers; Opisthorchis viverrini, hookworm, Strongyloides stercoralis, Giardia lamblia, Trichuris trichiura, Fasciolopsis buski, Taenia sp, Echinostoma sp, Entamoeba coli. METHODS: From June 1992 to December 1993, a total of 302 Thai laborers, participating in the mandatory entry health examination at Chang-Gung Memorial Hospital, Lin-Kou Medical Center were interviewed and examined. These subjects underwent a physical examination, chest roentgenography, and serological tests for human immunodeficiency virus antibody, syphilis (VDRL), and hepatitis B surface antigen. RESULTS: Among the 302 Thai laborers examined, 196 (64.9%) were found to be infected with 1 to 5 species of parasites. All 193 infected Thai laborers were treated in Taiwan. Two or 3 courses of pyrantel pamoate, mebendazole, praziquantel, and metronidazole were administered to 119, 45, 24, and 5 infected patients respectively. After 1 week of treatment, all results of stool examinations were negative. CONCLUSION: Acquisition of infection has been determined to be related to the consumption of koipla, a dish prepared from uncooked freshwater fish. Not unexpectedly, in the present study, it was found that this species was the most important intestinal parasite among Thai laborers and was significantly associated with the consumption of koipla.