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1.
Surg Case Rep ; 6(1): 256, 2020 Oct 02.
Artigo em Inglês | MEDLINE | ID: mdl-33006746

RESUMO

BACKGROUND: The concept of GIST was established in 1998, clearly differentiating between gastrointestinal leiomyosarcoma and GISTs among gastrointestinal mesenchymal tumors. Lymph node metastasis is extremely rare in true gastrointestinal leiomyosarcoma, and there are no reports of malignant transformation from leiomyoma. CASE PRESENTATION: The patient was an old woman who had undergone endoscopic mucosal resection for an Is polyp on the left side of the transverse colon at the age of 73. She was diagnosed with leiomyoma with positive surgical margins. Subsequently, she presented to our institution with a sensation of pressure in the upper abdominal region as a chief complaint at the age of 76 years. Abdominal computed tomography and colorectal endoscopy showed a tumor lesion with invagination of the intestines in the transverse colon, the same site as that of the previously resected leiomyoma. A biopsy suggested a smooth muscle tumor, and we performed partial left transverse colectomy and lymph node dissection under a diagnosis of recurrence and enlargement of the previously incompletely resected leiomyoma. Histopathological examination revealed spindle-shaped tumor cells, and the mitotic activity was 30-40/10 high-power field. Tumor cells were immunohistologically positive for α-smooth muscle actin and h-caldesmon; partially positive for desmin; negative for c-kit, CD34, DOG-1, and the S-100 protein; and showed a Ki-67 labeling index of 70-80%. She was diagnosed with leiomyosarcoma malignantly transformed from leiomyoma. Metastasis was found in 1 of the 14 resected lymph nodes. The patient did not undergo adjuvant chemotherapy, but has survived with no recurrence at 2 years after the surgery. CONCLUSIONS: We have reported a case of leiomyosarcoma of the transverse colon with lymph node metastasis that was malignantly transformed from a leiomyoma.

2.
Gan To Kagaku Ryoho ; 30 Suppl 1: 135-7, 2003 Dec.
Artigo em Japonês | MEDLINE | ID: mdl-14708318

RESUMO

We reviewed our cases of HPN and HEN after percutaneous gastrostomy. We had 38 patients (26 men, 12 women) on HPN. Of them, 23 (17 men, 6 women) had an implantable subcutaneous infusion port. The average age of HPN cases was 69 (range 40-92) years, and 34 patients (89%) suffered from a malignant disease. The mean duration of HPN was 104 (range 2-543) days. Home anti-cancer chemotherapy was provided for 2 patients. Percutaneous gastrostomy was performed for 7 patients (4 men, 3 women) by endoscopy (PEG, 6 cases) and 1 patient needed an open laparotomy. Their average age was 60 (range 40-83) years. 5 patients with a malignant disease who were in HPN underwent gastrostomy for decompression drainage of a digestive tract obstruction. 2 patients had a benign disease and were on HEN for a long time. We experienced 2 cases of skin complications, one under HPN and the other under HEN, but no severe complication experienced. HPN and HEN contribute to improve the patients' QOL.


Assuntos
Nutrição Enteral , Serviços Hospitalares de Assistência Domiciliar , Neoplasias/terapia , Nutrição Parenteral no Domicílio , Qualidade de Vida , Adulto , Idoso , Gastrostomia , Humanos , Avaliação de Estado de Karnofsky , Masculino , Pessoa de Meia-Idade
3.
Gan To Kagaku Ryoho ; 30(1 Suppl): 135-7, 2003 Dec.
Artigo em Japonês | MEDLINE | ID: mdl-15311785

RESUMO

We reviewed our cases of HPN and HEN after percutaneous gastrostomy. We had 38 patients (26 men, 12 women) on HPN. Of them, 23 (17 men, 6 women) had an implantable subcutaneous infusion port. The average age of HPN cases was 69 (range 40-92) years, and 34 patients (89%) suffered from a malignant disease. The mean duration of HPN was 104 (range 2-543) days. Home anti-cancer chemotherapy was provided for 2 patients. Percutaneous gastrostomy was performed for 7 patients (4 men, 3 women) by endoscopy (PEG, 6 cases) and 1 patient needed an open laparotomy. Their average age was 60 (range 40-83) years. 5 patients with a malignant disease who were in HPN underwent gastrostomy for decompression drainage of a digestive tract obstruction. 2 patients had a benign disease and were on HEN for a long time. We experienced 2 cases of skin complications, one under HPN and the other under HEN, but no severe complication experienced. HPN and HEN contribute to improve the patients' QOL.


Assuntos
Nutrição Enteral , Serviços de Assistência Domiciliar , Apoio Nutricional , Nutrição Parenteral no Domicílio , Adulto , Idoso , Idoso de 80 Anos ou mais , Nutrição Enteral/métodos , Feminino , Gastrostomia , Humanos , Bombas de Infusão Implantáveis , Masculino , Pessoa de Meia-Idade , Neoplasias/enfermagem , Nutrição Parenteral no Domicílio/métodos , Qualidade de Vida
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